Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"extracellular stimulation"”.
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Extracellular stimulation of individual electrogenic cells with micro-scaled electrodes
… investigations with multiple interfaces for extracellular recording and stimulation on a single-cell level are desirable to gain precise access to the network or tissue. The main focus of this work was to study the extracellular stimulation of individual electrogenic cells in vitro with …
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Calcium dynamics in dendrites and spines of spiny neurons in the somatosensory ‘barrel’ cortex of the rat
… when the action potential followed synaptic stimulation within less than 20 ms. The mechanism of maximal Ca2+ influx could be explained by the properites of the NMDA receptor channel, which was activated by binding glutamate during synaptic stimulation and subsequent relief of the Mg2+ block …
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Microsystem Based on CMOS Multielectrode Array for Extracellular Neural Stimulation and Recording
… circuitry. Conventional electrophysiological stimulation and measurement technique such as patch clamping have become the standard techniques for accurate stimulation and recording of electrical activities in neurons. Nevertheless, the number of electrodes that can be introduced into the …
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Directed Migration Achieved in Mammalian Cells via Ca2+ Signal Rewiring in Synthetic Protein Chimeras
… dynamic cellular blebbing to increases in extracellular free Ca2+. Next, we validated this design strategy in two systems, i.e., inflammatory cytokines such as TNFα and antibodies. A system of proteins was used: an engineered TNFα chimeric receptor (named TNFR1chi), a previously engineered …
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Multi-Scale Modeling for Analysis and Design of Transcranial Electric and Magnetic Brain Stimulation
<p>Transcranial electric stimulation (tES) and magnetic stimulation (TMS) can noninvasively modulate brain activity in humans, offering broad research and therapeutic applications. However, improving the efficacy and selectivity of these techniques is challenging without a mechanistic understanding …
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Auditory brainstem neurons as components of a biohybrid system
… excitatory postsynaptic potentials and APs after extracellular stimulation and recordings of miniature excitatory postsynaptic currents provided further evidence for synaptic transmission between neurons in the culture. This study demonstrates that the neurons from the avian auditory brainstem …
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Design, development and evaluation of a high spatial density CMOS chip for bidirectional communication with electrogenic cells
… selection of individual pixels for electrical stimulation. Further down on the signal path, a bank of 8 8-to-1 multiplexers were implemented on the right hand side of the 64 amplifiers to reduce the number of simulatenously read-out channels from 64 to 8. The outputs of the multiplexers were …