Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 33 for “"extracellular recordings"”.
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Selective attention and the visual representation of object attributes in the ventrolateral prefrontal cortex and anterior cingulate cortex of the rhesus monkey
… of that object were investigated using extracellular recordings. A female rhesus monkey performed a delayed match to object attribute (DMSA) task, in which she alternately matched object orientations and object colors. In half of the task conditions, only one attribute matched the …
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Adaptive multiscale biological signal processing
… attention toward ultrasound imaging and extracellular recordings. Original algorithms developed during the Ph.D. research activity will be examined and compared to ones in literature tackling the same problems; results will be drawn on the base of comparative tests on both synthetic and …
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Functional and Categorical Analysis of Waveshapes Recorded on Microelectrode Arrays
… to several weeks. The signature wave shapes from extracellular recording of neuronal activity display a great variety of shapes with triphasic signals predominating. I characterized extracellular recordings from over 600 neuronal signals. I have preformed a categorical study by dividing wave …
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Encoding of periodic skin stimuli by spinal dorsal horn neurons
… To accomplish this task, dorsal horn single unit extracellular recordings were obtained during periodic electrical and sinusoidal mechanical stimulation of their receptive fields. Techniques used in classifying vibrotactile pitch encoding were similar to those used in other somatosensory nuclei, …
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Eight Legs And A Brain: Locomotor Mimicry Of Ants And Neuroethology Of Jumping Spiders
… ants. Chapter 3 uses behavioral trials and extracellular recordings of electrical activity from neurons in the jumping spider brain to explore responses to airborne acoustic stimuli. This work demonstrates that jumping spiders perceive airborne sound at distances far greater than previously …
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Neural mechanisms involved in memory formation and retrieval within the rodent hippocampus : an in vivo electrophysiological study
… In this thesis I have combined large-scale recordings from multiple single cells within the hippocampus of behaving rodents with pharmacological and genetic manipulations of hippocampal function in order to investigate how the cellular and network properties of the hippocampus contribute to …
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The Murine Brain Slice as a Model for Investigation of Environmental Toxin Involvement in the Etiology of Parkinson's Disease
… were undertaken in murine striatal slices. Extracellular recordings of spontaneous nerve discharge were used to compare the effects of the cyclodienes and the prototypical GABA antagonist, picrotoxinin, upon striatal neurons. At low micromolar concentrations of cyclodiene, depression of …
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Small intestine slow wave activity defined through in vivo high-resolution electrical mapping
… as ideal filtering for small intestine slow wave recordings. An automated algorithm for marking slow wave activation times (ATs) was adapted and tuned for intestinal use, achieving a sensitivity of 0.87 0.04 and positive predictive value of 0.90 0.07. The quantitative data analysis and …
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LGN activity patterns during ocular dominance plasticity in vivo
… validated. Therefore, we performed extracellular recordings from the dLGN of animals during periods of visual manipulation. Contrary to previous hypotheses, the present findings demonstrate that MC does not alter the overall firing rate of neural activity in the dLGN. Instead, MC …
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Stress-Related Effects of Phoenixin on Nucleus of the Solitary Tract Neurons
… of both PNX and its receptor, GPR173. Using both extracellular and whole-cell current clamp recording techniques in a coronal NTS slice preparation, this study characterized the effects of PNX on both spike frequency and membrane potential of NTS neurons in order to determine neuronal effects of …
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Evidence for effects of phoenixin on neurons of the paraventricular nucleus
… of PNX on PVN neuronal activity using in vitro extracellular recordings. Recordings from a total of 824 neurons showed that 16% (n= 130) of these cells were activated by bath administration of PNX, while 14% (n= 117) were inhibited. Remaining cells tested showed no obvious changes in spike …
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Altered GABA ergic system in the posterior hypothalamus of the spontaneously hypertensive rat
… the hypothalamic GABAergic system. Single unit, extracellular recordings of posterior hypothalamic neurons were performed in both in vivo and in vitro preparations. The spontaneous firing rate of posterior hypothalamic neurons in anesthetized adult and young SHRs was significantly higher compared …
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Predictive decoding of neural data
… of results from four neural data modalities: extracellular recordings, EEG, MEG, and fMRI. These examples demonstrate the ability of the approach to reveal neural data components which cannot be uncovered with conventional methods. A further extension of the methodology, Chapter 4 is used to …
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Ground truth in ultra-dense neural recording
… there have been very few multi-electrode recordings done in concert with techniques such as patch clamp, which report the "ground truth" voltage state of a single neuron in a population. Such recordings would allow for the direct evaluation of spike sorting, which in turn could lead to …
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Top-down and bottom-up interactions for cortical bursting
… these questions, we performed high-density extracellular recordings in primary visual cortex of awake mice while presenting a battery of Gabor (bottom-up) and inverse (top-down) visual stimuli. We report widespread high-frequency bursts in L2/3 and L5 pyramidal neurons. Contrary to …
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Cerebellar Coordination of Neuronal and Behavioral Rhythms
… and dorsal CA1 (dCA1) using multisite in vivo extracellular recordings in freely moving mice. We compared a mouse model of cerebellar ataxia and their littermate controls. The ataxic mice were designed to have a genetically induced loss of Purkinje cell neurotransmission, resulting in an …
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The Neural Computations In The Caudate Nucleus For Reward-Biased Perceptual Decision-Making
… discrimination task and performed single-unit extracellular recordings in the caudate nucleus, the input station in the basal ganglia. Fitting the monkeys’ behaviors to a drift-diffusion model, we found that the monkeys used a rational heuristic to combine sensory and reward information. This …
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Plasticity of Brainstem Motor Systems in Response to Developmental Nicotine Exposure
… experiments, we used whole cell patch clamp recordings from XIIMNs in a transverse slice of the medulla, and extracellular recordings from the 4th cervical ventral root in the brainstem spinal cord, split bath preparation. All preparations were obtained from control or DNE neonatal rats in …
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"""White Noise"" Non-Linear Analysis of Inferior Colliculus Neural Responses in the Little Brown Bat, Myotis Lucifugus"
… detection of inhibition (despite the use of extracellular recordings) and of delay-sensitive facilitation (in 11% of IC neurons). These response features could not have been determined using standard techniques unless numerous different experiments were carried out to specifically investigate …
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The Neuronal Basis of Signal Detection in the Presence of Spatially Separated Noise: A Study in the Frog Inferior Colliculus
… mates calling in a dense heterospecific chorus. Extracellular recordings were made from single auditory units in the inferior colliculus (IC), while the frog was subject to free-field stimulation with sinusoidally amplitude modulated tone bursts (signal) in the presence of spatially separated …
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