Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 44 for “"external-beam"”.
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Characterizing canine dose from external beam irradiation
Absorbed dose from Computed Tomography (CT) is a major concern on an individual basis as well as for the collective population due to increased frequency of and dependency on CT scans for diagnostic and therapeutic imaging. Colorado State University recently integrated a large bore multi-slice …
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Convex and Robust Optimization Methods for Modality Selection in External Beam Radiotherapy
The goal in external beam radiotherapy (EBRT) for cancer is to maximize damage to the tumor while limiting toxic effects of radiation dose on the organs-at-risk (OAR). EBRT can be delivered via different modalities such as photons, protons, and neutrons. The choice of an optimal modality depends on …
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In Vivo Dosimetry Using Plastic Scintillation Detectors For External Beam Radiation Therapy
… not been used for <em>in vivo </em>dosimetry of external beam radiation therapy to date. The overall purpose of this work is to apply PSDs to <em>in vivo</em> dosimetry of external beam radiation therapy, and demonstrate the utility and practicality of performing <em>in vivo </em>dosimetry with …
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The overall survival and local control benefit of external beam radiation therapy for selected cancers
Background: The population benefits achievable with optimal access to radiotherapy in Australia are unknown. This information would be of use for planning, priority setting, and economic analysis. Methods: 5-year local control (LC) and 2-year and 5-year overall survival (OS) benefits were …
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Multienergetic External-beam PIXE as a Means of Stydying the Surface Enrichment Effect in Coins
… thesis paper examines the feasibility of using external-beam PIXE to study the surface enrichment effect in metal artifacts. By varying the energy of the incident proton beam, we penetrated the artifact's surface to different levels and were able to produce a depth profile of the elemental …
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MODEL OF ESTIMATION OF LOCAL CONTROL AND SURVIVAL BENEFIT OF EXTERNAL BEAM RADIOTHERAPY FOR SELECTED CANCERS
Aims The aim of this study was to estimate the population-based local control (LC) and overall survival (OS) benefits of radiotherapy for selected cancers if the whole cancer population in Australia were treated according to evidence-based guidelines. These estimates were based on the published …
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The role of magnetic resonance imaging (MRI) in external beam radiotherapy treatment planning (RTP) for cervical cancer
… of data for the role of MRI in delineating external beam radiotherapy treatment volumes. Aims 1) Quantify the proportion of women with cervical cancer in whom there is evidence to support the use of MRI for radiotherapy planning (RTP), 2) Evaluate the effect of an educational intervention on …
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Evaluation of target motion and determination optional treatment margins for prostate cancer treated with external beam radiotherapy on Halcyon
Background External beam radiotherapy (EBRT) is an important part of the treatment for prostate cancer. To account for organ motion and set-up error, margins are used in radiotherapy planning. These are essential for the delivery of safe and effective treatment. Aim and Setting To measure prostate …
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Quantitative Comparison of Late Effects Following Photon Versus Proton External-Beam Radiation Therapies: to ward An Evidence-Based Approach to Selecting A Treatment Modality
<p>Radiation therapy has been used as an effective treatment for malignancies in pediatric patients. However, in many cases, the side effects of radiation diminish these patients’ quality of life. In order to develop strategies to minimize radiogenic complications, one must first quantitatively …
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Investigating a novel combination treatment of androgen deprivation therapy, pelvic external beam radiotherapy and radium-223 dichloride in the management of hormone sensitive prostate cancer metastatic to bone
… including docetaxel and abiraterone as well as external beamradiotherapy (EBRT) to prostate (in low volume disease). We wished to test thenovel combination of concurrent radium-223 + EBRT to prostate and pelvic lymphnodes in mHSPC. </p><p class="MsoNormal" …
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Prevention of Radiation-Induced Skin Reactions in Breast Cancer External Irradiation
Radiation dermatitis is a common side effect of external beam radiation therapy. The purpose of this study was to evaluate the effectiveness of applying an aloe vera based skin gel to the target area skin in preventing the development of radiation dermatitis to postlumpectomy/ mastectomy patients …
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Feasibility of Using Stereotactic Body Radiation as an Alternative to HDR for Treatment of Cervical Cancers
… a linear accelerator. The possibility of using external beam radiation therapy utilizing a Stereotactic Body Radiation Therapy (SBRT) or Intensity Modulated SBRT (IM-SBRT) approach was evaluated in this project. Method and Materials: Volumes covered by the HDR prescription were used to define a …
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Protein engineering for targeted delivery of radionuclides to tumors
… strategies include systemic chemotherapy, external beam radiation, and surgical excision. Chemotherapy is nonspecific, and targets all rapidly dividing cells. External beam radiation and surgery only target known cancer sites. However, targeted therapeutics, such as antibodies, will bind to …
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Improving Cervical Cancer Nodal Boost Radiation Therapy By Quantifying Uncertainties and Exploring Advanced Radiation Therapy Modalities
… cancer is frequently delivered using primary external beam radiation therapy (EBRT) followed by two fractions of intracavitary brachytherapy (ICBT). Although the tumor is the primary radiation target, controlling microscopic disease in the lymph nodes is just as critical to patient treatment …
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Application and Development of Algebraic Reconstruction Algorithms for High Dose Rate Brachytherapy Gel Dosimetry with Optical Computed Tomography Readout
… requires more thorough quality assurance (QA). External beam radiation therapy has seen an increase of QA of individual patients’ treatments for complex deliveries. This is known as patient specific quality assurance. High dose rate (HDR) brachytherapy treatments have become more complex, but …
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Segmented breast treatment planning incorporating 4D data acquisition
Conventional 3-D external beam radiation therapy for breast cancer, although a vast improvement over traditional therapy, does not take into account respiratory motion. With breast cancer patients, this motion can expose healthy tissues, such as the lungs, to higher doses than expected. More …
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Construction of a model for the improved planning of MCO-informed VMAT in RayStation using a knowledge base of clinical IMRT-MCO treatment plans
… Modulated Radiation Therapy (IMRT) is a type of external beam radiation therapy that has proven effective at treating many cancers. A related therapy type, Volumetric Modulated Arc Therapy (VMAT), has the potential to provide comparable dose coverage to tumor sites while better sparing nearby …
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The role of nucleotides and the P2X7 receptor in radiation induced bystander effect
… to display the bystander effect following external beam radiation therapy. Additionally, the purinergic receptor P2X7 was targeted in order to study the effects of inhibiting this receptor on the bystander effect Method: The cell line UVW/NAT was used in these experiments. One group of …
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Continuous low dose rate irradiation of the rat brain
… with the use of continuous low dose rate external beam radiotherapy, where the treatment is administered over a 12 to 24 hour period. A relationship between fractionated and continuous low dose rate irradiation has been reported for skin, however, no such relationship has been reported for …
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