Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 320 for “"expression pattern"”.
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Expression pattern and role of Foxcl during hair follicle morphogenesis
… tissues, relatively little is known about the expression and role of this gene in the skin. To determine the Foxe] expression pattern during embryonic and neonatal skin development, this study utilised mice in which the Lac-z reporter gene was placed under the control of wild-type Foxcl …
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Characterization of Prolylcarboxypeptidase Expression Pattern in Rat Cardiomyocytes in Nutrition Overload Conditions
… of mortality in diabetes and obesity, PRCP overexpression in nutrition excess conditions represents an important target for studying metabolic syndrome- related cardiac dysfunction. The overall goal of this study was to elucidate the hormetic effects of major nutrients on PRCP-dependent …
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Characterizing the Expression Pattern of miR167-Regulated ZmArf3 and ZmArf30 in Maize Inflorescences
… inflorescences, the tassel and ear, which are patterned by a series of branching events that depend on the initiation of axillary meristems. The maize fuzzy tassel (fzt) mutant contains a mutation in dicer-like1, a key enzyme require for microRNA (miRNA) biogenesis in plants. MiRNAs small …
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Expression Pattern of Drug-Resistance Genes in Matched Clinical Isolates of Candida albicans at Variable Fluconazole Exposure Times
… isolates, resistance to FLC is due to overexpression of a) the encoding genes CDR1 and CDR2 for the ABC Transporters, b) the Major Facilitator Transporter encoding gene MDR1, or c) ERG11, the azole target gene. Previous studies have shown gene expression in a matched set of clinical …
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Localisation and expression pattern of the Nogo receptor and its ligand, Nogo-A in cells of the mammalian central nervous system
… major aim of the study was to investigate the expression pattern of Nogo receptor and one of its ligands, Nogo-A in the mammalian nervous system, and also investigate whether Nogo receptor is located in neuronal lipid rafts by linking it to flotillins, known lipid raft markers. We therefore …
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Automation of Drosophila gene expression pattern image annotation : development of web-based image annotation tool and application of machine learning methods
… are providing an abundance of spatio-temporal patterns of gene expression data that is valuable for understanding the mechanisms of gene regulation. Drosophila gene expression pattern images have been generated by the Berkeley Drosophila Genome Project (BDGP) for over 7,000 genes in over 90,000 …
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Comparison of expression pattern and localization of iron transport proteins in rat liver, brain and spleen during acute phase response:invivo and invitro studies
… genaue Mechanismus, und die Veränderungen der Genexpression und Lokalisierung der Proteine in der Eisen-Regulation beteiligt sind noch nicht vollständig geklärt. Aktuelle Studie sollte die Ausdrucksmittel Änderungen und unterschiedliche Lokalisation der Eisentransportproteine zu vergleichen, …
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Correlation between the expression of integrins and their role in cancer progression. Expression pattern of integrins αvβ3, αvβ5 and α5β1 in clinical and experimental tumour samples
… angiogenesis. It has been shown that integrin expression is positively correlated to cancer dissemination, this suggests targeting selected integrins as an anti-metastatic strategy. The aim of this study is to investigate the effect of novel antagonists of α5β1, αvβ3 and αvβ5 integrins on …
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Characterization of a Novel Water Stress Related Protein from Geranium (<em>Pelargonium hortorum</em>).
… <em>Arabidopsis</em> 4-CL primers were used for expression analysis by RT-PCR of <em>Arabidopsis</em> 4-CL mRNA from <em>Arabidopsis</em> root tissue. The expression pattern of the <em>Arabidopsis</em> 4-CL mRNA was identical with the expression pattern of the mRNA that hybridized with the …
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Evolution of the ZRS and the Regulation of SHH Expression in the Forelimbs of Bats.
… and Carollia perspicillata showed that Shh expression pattern was different from that observed in mouse limbs. An interesting discovery was that bat embryos display a second round of expression at stage CS16/E12.5. The aim of this thesis is to investigate the cause of the Shh expression …
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Expression von CNTFRalpha in humanem Muskel- und Nervengewebe
… of peripheral nerves. In this study the expression pattern of the specific CNTF binding entity (CNTFR() in human tissue (muscle and nerve) was analyzed. By in situ hybridization the transcribed RNA could be detected in paraffin section. In muscle biopsies, the CNTFR( transcripts were …
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Differential Expression Analysis of Type II Toxin-Antitoxin Genes of Pseudomonas aeruginosa PAO1 under Different Environmental Conditions
… presence, no studies have shown the differential expression pattern of its toxin-antitoxins, and persistence related genes. The purpose of the following study is to analyze differential expression of P. aeruginosa PAO1 type II toxin-antitoxins and persistence related genes under different growth …
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Organophosphorus Pesticide Exposure Effects on Neurobehavioral Development of Zebrafish and Characterization of Developmental Switch Between Two Cation-chloride Cotransporters (zfnkcc1 and zfkcc2)
… we were able to characterize its expression pattern up to 4 dpf. Using qRT-PCR, we showed that the expression of <italic>zfkcc2</italic> rises from 2 to 96 hours post fertilization (hpf). The expression of <italic>zfkcc2</italic> is found at 1 dpf in the forebrain, midbrain and …
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Interaction of akirin and pannier during embryogenesis of Drosophila melanogaster
… </em>regulatory elements by studying their expression pattern in <em>Drosophila melanogaster</em>. Acknowledging <em>pannier’s</em> role in the early stages of somatic muscular development, a genetic cross of <em>akirin/pannier</em> double heterozygous mutant embryos were imaged to visualize …
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Potential roles for Elf3 in fetal alcohol spectrum disorder and development
… exposure. We also give some insight into the expression pattern of elf3 in relation to zygotic genome activation. Translation blocking morpholino oligonucleotides were used to implicate Elf3 in epiboly movements during gastrulation and zebrafish tail development. Taken together these results …
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Analysis of HOXA5 expression and function in development of the central nervous system
… are indispensable for proper spatio-temporal patterning of the vertebrate body axes. In mouse, Hoxa5 transcripts are differentially expressed in specific mesoderm-derived structures and in the most anterior domain of expression in the central nervous system (CNS). However, the functional …
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Discovery of the novel mouFSnrp gene and the characterisation of its in situ expression profile during mouse neurogenesis
… mouFSnrp gene, and the characterisation of its expression pattern and ontogeny during mouse neural development. Through the work described in this thesis, the mouFSnrp gene was identified in mouse embryonic cortical cultures and its protein coding gene sequence was verified. mouFSnrp expression …
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