Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"expression cloning"”.
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Facial Expression Cloning with Fuzzy Membership Functions
… and experimental results of a system to explore cloning of facial expressions between dissimilar face models, so new faces can be animated using the animations from existing faces. The system described in this thesis uses fuzzy membership functions and subtractive clustering to represent faces …
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Expression cloning and characterization of the type II and type III TGF-β receptors
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1993.
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Expression, Cloning, and Sequencing of Putative Insulin Signaling Genes Involved in Diapause in the Flesh Fly <em>Sarcophaga crassipalpis</em>.
… and aging programs have a common set of gene expression pathways via insulin signaling. Analysis of a heterologous microarray indicated that two genes involved in the insulin pathway were down regulated during diapause. Both of these genes, Pi3K68d and Pde6, along with the Insulin receptor …
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Entwicklung und Anwendung eines Expressionsklonierungssystems in primären Kardiomyozyten - Identifizierung von Translin als neuem Target der Herzinsuffizienz
Development of an expression cloning system in primary cardiomyocytes - Validation of Translin as a new target for heart failure Congestive heart failure continues to represent a life threatening disease with unmet medical need. Functional impairment of the insufficient heart is reflected in …
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Regulation of Cell Migration by Integrin -Mediated Adhesion
… cell migration. The technique of mammalian cDNA expression cloning was used to identify regulators of cell-substratum adhesion. Through this approach, a cDNA with homology to RACK1, a receptor for activated protein kinase C, was identified. Interestingly, this cDNA was found to be a truncated …
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Cloning and characterization of novel kinases from embryonic cells.
… Attempts to identify novel PYKs through expression cloning strategies have led to the identification of a novel family of protein kinases, referred to as dual specificity kinases (DSKs). In addition to their immunoreactivity with antiphosphotyrosine antibodies, DSK family members have the …
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Molecular expression and immunotherapeutic potential of the novel tumour associated antigen T21
… tumour antigen identified using modified SEREX expression cloning showing restricted protein expression to normal testis and prostate, breast, kidney, ovary, melanoma, colon and stomach cancer among others. More recently, T21 was found to share significant sequence similarity with a centrosomal …
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Identification and Biochemical Characterization of Ghrelin O-Acyltransferase (GOAT)
… had remained elusive for nearly a decade. By expression cloning, I have identified GOAT (Ghrelin O-Acyltransferase), an enzyme belonging to a family of 16 polytopic membrane-bound O-acyltransferases. GOAT activity requires catalytic Asn and His residues, which are conserved through …
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Casein Kinase I Transduces WNT Signals
… of this signal transduction pathway via expression cloning in Xenopus embryos. This assay identified a protein kinase, casein kinase I (CKI), as a novel component of the Wnt signaling pathway. We first showed that expression of CKI produces Wnt phenotypes. First, CKI induced completely …
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Analysis of Aurora B Regulation and Signaling
… screened Aurora B substrates using an in vitro expression cloning system. However, the methodology we employed didn't lead to candidate substrates to be further validated by more rigorous in vivo approaches. The use of high concentrations of misfolded recombinant Aurora B was partially …
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Automatic 3D facial modelling with deformable models.
… by reusing existing data. One example is expression cloning, which copies facial expression from one face to another instead of creating them from scratch. This aim of this study is to develop a fully automatic framework for template-based facial modelling, facial expression transferring …
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Molekulare Mechanismen der Regulation von Matrixkontakten und Migration melanozytärer Zellen durch das Protein MIA
… of cellular signaling pathways and on the MIA-expression regulatory pathways. All melanoma cell lines show a strong expression of MIA protein. MIA interacts with proteins of the extracellular matrix (ECM), specifically with fibronectin and laminin. Subsequently it masks the binding sites for …
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Differentielle Genexpressionsanalyse aktivierter Endothelzellen
… Verfahrens wurde eingesetzt zur genetischen Expressionsanalyse aktivierter Endothelzellen als in vitro-Modell für die Biologie der Angiogenese, der Sprossung von Blutgefässen aus bereits bestehenden. Dabei kam ein zweidimensionales in vitro-Modell boviner Aortenendothelzellen (BAEC) zum …