Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"exposure-response relationships"”.
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Exposure-response relationships from railway noise in the presence of vibration
The main aim of this thesis is to develop exposure-response relationships for noise,vibration, and combined effects from noise and vibration. Examinations of nonacousticalfactors such as noise sensitivity, noise acceptance, gender, age, and sleepdisturbance are also performed in this project. Many …
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Human response to railway vibration in residential environments : exposure-response relationships and modifying factors
… aims to contribute to the knowledge of human response to vibration inresidential environments and identify factors of primary importance whenconsidering exposure-response relationships from railway vibration. It has previouslybeen shown that annoyance increases with vibration magnitude. …
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Evaluation of Dose-Exposure-Response Relationships of Miltefosine and Discovery of Multicomponent Crystal Forms of Artesunate
… the drug is associated with differences in exposure patterns and cure rates among different population groups e.g. ethnicity and age (i.e., children v adults) in clinical trials. Artesunate (ATS), a BCS class II drug widely used for anti-malaria therapy, exhibits not only poor solubility but …
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Exposure, health effects, immunological markers and biomarkers of susceptibility among Swedish rubber workers
… cancer and probably cardiovascular disease. The exposure is very complex; carbon disulfide (CS2) and polycyclic aromatic hydrocarbons (PAHs) being two of the contaminants. The general aim of this thesis was to find exposure-response relationships usable for risk assessments in the rubber …
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Development and Evaluation of Methods to Assess Physical Exposures in the Workplace
… Accurately quantifying the level of physical exposures (i.e., kinematics and kinetics) is essential for risk assessments, developing and/or testing interventions, and improving estimates of exposure-response relationships. Such exposures ideally should be quantified in situ, while workers …
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Long-Term Ambient Ozone Exposure: Magnitude, Trends, and Impacts
<p>Long-term exposure to ambient ozone (O3) is associated with a variety of impacts, including adverse health effects in humans (U.S. EPA 2013) and reduced yields in commercial crops (Chameides et al., 1994; Mauzerall and Wang, 2001). Due to such impacts, efforts have been undertaken in recent …
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Adjusting retrospective noise exposure assessment for use of hearing protection devices
Earlier retrospective noise exposure assessments for use in epidemiological research were not adequately characterized because they did not properly account for use of hearing protection devices (HPD) which would result in potential misclassification. Exposure misclassification has been shown to …
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The study of occupational risk factors and interventions for baker's allergy and asthma among supermarket bakery workers
… characterise asthma phenotypes and environmental exposure to flour allergens among bakers and modifying factors; study associations between phenotype and environmental exposure and identify potential modifying factors of this association; determine the effectiveness of specific interventions in …
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Model-Informed Drug Development of Riluzole for Neuroprotection in Acute Spinal Cord Injury: Integrating Pharmacokinetics, Pharmacodynamics, and Clinical Outcomes for Precision Medicine
… and guide individualized treatment based on drug exposure, biomarker response, and recovery profiles. The first objective involved exploring clinical responses to riluzole through comprehensive exploratory data analysis using the RISCIS PK sub-study dataset. Results indicated that individuals with …
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Opportunities and Challenges in Identification and Classification of Heat Stress Risk Based on Analysis of Individual and Neighborhood Level Factors
… via wearable sensors will allow more accurate exposure assessment and identification of factors associated with dangerous exposures to extreme heat. The goal of this dissertation is to characterize the individually experienced heat index exposure via wearable sensors in an urban and a rural …
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Optimising linezolid use for drug-resistant tuberculosis: pharmacokinetics, toxicity, and resistance
… which could increase the risk of toxicity. Exposure-response relationships for linezolid toxicity are also not well characterised. In addition, limited data exist on clinical associations and genotypic correlates of linezolid resistance in M. tuberculosis, needed to inform strategies for …
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Risk factors for work-related asthma in health workers with exposure to diverse cleaning agents in two African health care settings
… limited information exists regarding exposure-response relationships between the frequency of exposure to specific cleaning agents and asthma-related outcomes. This study investigated the prevalence and risk factors for work-related asthma (WRA) among HWs exposed to diverse cleaning …