Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"experimental infection"”.
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Influence of body condition and homo- vs. heterosubtypic immunity on influenza A virus infection in mallard ducks : experimental infection data
… the global spread of influenza A viruses (IAVs). Experimental infection studies are used to assess a bird's ability to maintain IAV, but these studies have not represented the natural variation in physiological condition observed in migrating waterfowl and have only used captive-bred birds. We …
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Single and dual experimental infection of specific pathogen-free Litopenaeus vannamei shrimp with White Spot Syndrome Virus and Vibrio species
… stress, SPF shrimp became susceptible to infection by Vibrio through injection of 106 CFU shrimp-1 after an initial ammonium stress of 50 mgL-1 during 12 h, followed by a continuous ammonium exposure to 20 mgL-1. Another factor, namely WSSV burden, was used as interfering factor in testing …
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Isolation, Characterization, And Application Of Novel Bacteriophages For Preventing Experimental Infection With Mycobacterium avium subspecies paratuberculosis (MAP) Of Dairy Calves
… offer promise in controlling mycobacterial infections. Isolating new MAP-lysing bacteriophages is a crucial step toward implementing phage-based JD control. In pursuit of novel mycobacteriophages for JD control, we optimized an isolation protocol involving fecal spiking and varied isolation …
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Experimental infection with Sarcocystis neurona alters the immune response: the effect on CD4+, CD8+, B-cell, monocyte and granulocyte populations in horses
… immune deficiencies associated with S. neurona infection. We hypothesized that PMA/I stimulated suppression in EPM horses is due to decreased proliferation of monocytes, CD4+ and CD8+ cells. Our objectives were 1) to determine whether S. neurona infection causes an increase in apoptosis of a …
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A clinico-pathological study of schistosomiasis in South Central Africa.
… Egypt in this connection is that Fairley on the experimental infection of monkeys, which he published in 1920. Elsewhere in Africa, a number of smaller publications dealing with a particular or restricted clinical branch of schistosomiasis has been contributed by various authors, notably from …
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ΕΡΕΥΝΑ ΠΑΝΩ ΣΤΗ ΣΥΜΒΟΛΗ ΤΩΝ ΑΓΡΙΩΝ ΚΥΝΙΔΩΝ ΣΤΗΝ ΕΠΙΖΩΟΤΙΟΛΟΓΙΑ. ΕΠΙΔΗΜΙΟΛΟΓΙΑ ΤΗΣ ΕΧΙΝΟΚΟΚΚΙΑΣΗΣ ΥΔΑΤΙΔΩΣΗΣ ΣΤΗΝ ΕΛΛΑΔΑ
… OBJECTIVES: ONE EPIZOOTOLOGICAL AND THE OTHER EXPERIMENTAL. NO ADULT IMMATURE WORM OF ECHINOCCOCUS SPP WAS FOUND IN THE INTESTINES OF THE 580 FOXES; THE 11 JACKALS AND THE 4 WILD CATS EXAMINED. MATURE ADULTS E. GRANULOSUS WERE FOUND IN 4 OUT OF THE 28 WOLVES EXAMINED (I.E. INCIDENCE 14,2%). THE …
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Effects of Dietary Immunomodulation on Parasite Load in Commercial Crossbred Lambs
… sheep to clear a Haemonchus contortus infection. To test this hypothesis, Dorset-Texel lambs were fed a ration including CelmanaxRTM at 1g/hd/day for one week prior to receiving an experimental infection of 10,000 L3 stage H. contortus larvae; which continued until the completion of the …
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Protein FOG at the interface between G streptococci and human host defence lines
… equisimilis most commonly cause human GGS infections. These bacteria are part of the normal flora, but can cause pharyngitis, erysipelas and impetigo. In the immunocompromised host severe conditions, such as sepsis and necrotising fasciitis, may develop. In this thesis the interactions …
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Increased Severity of Murine Infection with Toxioplasma Gondii Following Vitaman E and Selenium Supplementatoin
… is one of the most common opportunistic infections in immunocompromised patients. The need for a reliable experimental model is crucial not only for achieving a better understanding of the pathophysiology of this infection but also for developing a better method to evaluate new …
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The role of gylcoprotein K (gK) in the ocular and neuropathogenesis of herpes simplex virus-type 1 (HSV-1)
… of humans. The hallmark of the HSV-lifecycle is infection of a mucosal surface with spread to sensory neurons where the virus establishes a latent infection with periodic recurrences for the life of the host. The most common course of symptomatic disease with HSV-1 is the typical mucocutaneous …
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The Role of Urease in the Pathogenesis of Edwardsiella ictaluri
… persistence, and for the ability to establish infection in a competition challenge during co-infection with the wild type (WT) strain. In an experimental infection of channel catfish macrophages, the ureG mutant strain was attenuated for intracellular replication while the WT strain showed more …
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The pathogenesis of EHV1 in horses : novel insights from experimental inoculations and field situations
… system disorders with frequent fatal outcome. Infection occurs via respiratory route and after local replication in tissues of the upper respiratory tract, the virus spreads via a cell-associated viremia to target internal organs such as the uterus or the nervous system. Secondary replication …
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The Molecular Characterization of Phosphorylcholine (ChoP) on Histophilus somni Lipooligosaccharide: Contribution of ChoP to Bacterial Virulence and Pathogenesis
… of the host respiratory tract was also examined. Experimental infection in the natural host showed that the population of H. somni that expresses ChoP was enriched in the bacteria that colonized the respiratory tract. In addition, bacteria expressing ChoP were able to aggregate bovine platelets …
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Cell tropism of maedi-visna virus
… the CNS (visna). The primary target cells of MVV infection in vivo are cells of the monocyte/macrophage lineage. However, certain MVV strains can infect various other cell types in vitro and by experimental infection in vivo. It has been shown previously that a repeated sequence in the LTR of MVV …
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Elucidating Mechanisms of Immunity to Nipah Virus Infection through Generation of Attenuated Viruses and a Single-Cycle Vectored Vaccine
… modulate the host innate immune response to NiV infection. Previously, ferrets infected with a recombinant NiV (rNiV) lacking V survived an otherwise lethal NiV challenge via an unknown mechanism. Mutation of the V gene of the related canine distemper virus prevented binding of V protein to …
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Insights Into Determinants That Contribute to Colonization, Virulence and Antibiotic Resistance In Enterococci
… increasingly common as causative agents of human infections, many of which are very difficult to treat due to multi-drug resistance. The work presented in the first part of this dissertation elucidates a mechanism for the regulation of pilus expression. I showed that ATT is the initiation codon of …
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Investigation of Immune Response to Sarcocystis neurona Infection in Horses with Equine Protozoal Myeloencephalitis
… the protective or pathologic immune response to infection to the intracellular protozoa S. neurona. The objective of these studies was to determine the effects of S. neurona infection on the immune response of horses that had EPM due to natural infection (experiment 1) and experimental infection …
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Analysing M. avium-macrophage interactions and establishing a long-term infection in a novel and realistic model of lung alveolar macrophages, Max Planck Institute Cells
… thus assisting MAC in the spread of infection. It is vital that these mechanisms are investigated so that the disease process is better understood, and therapeutic strides are made. There is a need for developments in the therapeutic pipeline due to the influx of multi-drug resistant …
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Characterisation of Streptococcus pneumoniae opacity phase variation
… at the Type I RM locus also occurred during experimental infection. However, there were inconsistencies between the opacity phenotypes of locked mutants and the RM allele distribution in wild-type D39O and D39T. Thus, RM allele switching cannot fully account for colony opacity phase variation …
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