Global ETD Search
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Showing 1 to 4 of 4 for “"exocytic machinery"”.
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Packaging and Secretion of Airway Mucins
… Formation of the complex drives fusion of the exocytic vesicle with the plasma membrane. These SNARE interactions take place on a scaffold provided by a Munc18 protein. Prior work in the Dickey-Tuvim laboratory has shown that different Munc18 proteins mediate baseline and stimulated mucin …
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Syntaxin-3 mediates baseline and stimulated mucin secretion
… isoform remains unknown.</p> <p>Three candidate exocytic Stx, 3, 4, and 11, were localized using immunofluorescence microscopy. To determine function, cell-specific deletion in club cells was accomplished by crossing the Stx mutant/floxed mice to Scgb1a1tm1(icre)fjd or tamoxifen-inducible …
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Vesicle-associated Membrane Proteins in Airway Mucin Secretion
… will contribute to identifying the baseline exocytic machinery. </p>
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Identifying the Role of Phospholipase D1 and Phosphatidic Acid in Exocytosis
… phosphatidic acid (PA), are involved in multiple exocytic processes. However, PLD1 and PA’s role in this process has remained unclear. In this work, PLD1 and the production of PA were visualized during exocytosis, and PA localization to regions of membrane curvature was established. Together, …