Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"excitatory neurotransmitters"”.
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Regulation of Endogenous Excitatory Neurotransmitters by Isoprostanes
… (IsoPs) regulate exogenously applied excitatory amino acid neurotransmitter glutamate in bovine retina, in vitro. However, the regulation of retinal endogenous glutamateby IsoPs is unknown. The objective of the present study was to investigate the effect of 8-isoprostaglandin E2 …
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The synthesis and pharmacology of some novel excitatory amino acid analogues
… L-aspartate, are believed to fulfil a role as excitatory neurotransmitters in the mammalian Central Nervous System (CNS). Investigation has revealed the presence of three, and possibly a fourth, type of receptor for such neurotransmitters. These receptors have been named after the most potent …
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A study of ultra-high field strength structural and spectroscopic MR imaging in dementia with Lewy bodies and Alzheimer’s disease
… (GABA) and glutamate (the primary inhibitory and excitatory neurotransmitters in the brain) may be related to visual hallucinations and cognitive fluctuations, though these analyses were exploratory and findings tentative. In summary, 7T-DLB is a novel study as it uses a relatively new technology …
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Regulation of Cerebellar Purkinje Cell Development: Interactions Between Trophic Factors and Neurotransmitters
… cell ontogeny, I studied the effects of NGF and excitatory transmitters on Purkinje cell survival and morphological maturation in dissociated cell culture. Purkinje cells were identified by expression of Vitamin D-dependent Calcium Binding Protein (CaBP), and by their characteristic morphology. …
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Role of galanin in synaptic transmission and plasticity in the CA1 area of the rodent hippocampus
… galanin seems to have a modulatory effect on excitatory neurotransmitters in the hippocampus, such as glutamate, thereby delaying the neurodegenerative effect of age. The research described in this thesis is deemed of importance in biomedical research of drug therapy for protection against …
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Newly Synthesized Pyroglutamate Amide and its Neuroprotective Effect Against Neurotoxicity Induced Cell Death in Alzheimer's Disease
… a phenomenon that describes the toxic actions of excitatory neurotransmitters, primarily glutamate, where the exacerbated or prolonged activation of glutamate receptors starts a cascade of neurotoxicity leading to the cell death. One of the most common neurodegenerative disorders is Alzheimer’s …
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MAPK and pro-inflammatory mediators in the walls of brain blood vessels following cerebral ischemia
… of ion homoeostasis, excessive release of excitatory neurotransmitters such as glutamate, calcium channel dysfunction, generation of oxidative stress and free radicals, activation of stress signaling, cell membrane disruption, inflammation, ultimately leading to necrotic and apoptotic cell …