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Showing 1 to 20 of 329 for “"excision"”.
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Excision of CTnDOT
Item withdrawn by Mark Zulauf (zulauf@illinois.edu) on 2013-01-24T19:34:21Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 2 Keeton_Carolyn.docx: 6779335 bytes, checksum: 32b917b01d2ce2946ce4c38114fe84a2 (MD5) Keeton_Carolyn.pdf: 4011034 bytes, …
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The Choreography of Base Excision Repair
… cells utilize DNA repair pathways such as base excision repair (BER). BER is carried out by a series of DNA repair proteins that function in a step-by-step process to identify, remove, and replace a damaged nucleotide. BER is critical to genome stability and cell survival, but unfortunately …
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Metabolic Modulation Of Mammalian Dna Excision Repair
… of a variety of metabolic factors on DNA excision repair was examined in studies involving measurements of damaged base removal, repair replication, and size of the resulting resynthesized regions or repair patches.;First, ultraviolet light (UVL)- and dimethylsulfate (DMS)-induced excision …
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Base excision repair, folate deficiency and cancer
… affects the DNA damage inducibility of base excision repair pathway. Our study shows the differential effect folate deficiency has on the expression of the genes involved in this pathway. Further, our study shows the increase in preneoplastic lesions in the colon of mice exposed to folate …
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Excision of the Bacteroides Conjugative Transposon CTnDOT
In this study, we showed that expression of the exc operon is regulated by tetracycline and mediated by the regulatory proteins, RteA, RteB, and RteC. Tetracycline induces the expression of rteA and rteB, genes in the tetQ operon. Then, RteB induces the expression of rteC. RteC, subsequently, …
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Integration and Excision Mechanism of Bacteroides Conjugative Transposons
… host. Whether RteB regulates CTnDOT and NBU1 excision directly or not is investigated in this study. Both RteB and the mutant are over-expressed in E. coli and partially purified. RteB is a soluble protein and gel shift result shows that RteB binds to 168bp upstream of rteC promoter region. …
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Positive regulators of Bacteroides CTnDOT excision and transfer
Tetracycline stimulates both excision and transfer of a Bacteroides Conjugative transposon CTnDOT. It was shown previously that a gene, rteC, is necessary for tetracycline-stimulated transcriptional regulation of the xis2c operon, which contains the excision genes. The protein encoded by this gene, …
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Minimally invasive CT-guiding excision of benign bone tumours
… techniques such as image guided intralesional excision and percutaneous radiofrequency ablation. We aim to evaluate the outcomes of patients treated with computerised tomography (CT guided) intralesional excision and bone grafting of small benign lesions of bone. Method: A retrospective folder …
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Recombination and Excision: DNA Repair Proteins in Prokaryotic Host-Virus Conflicts
… DNA repair, specifically recombination and base excision, have been co-opted by phages and bacteria to execute non-canonical immune and counter-immune functions in prokaryotic host-virus genetic conflicts. CRISPR-Cas adaptive immune systems, found in nearly half of all bacteria, use …
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The Integration and Excision Mechanisms of the Bacteroides Conjugative Transposon CTnDOT
A critical requirement for studying transposition is the availability of a defined in vitro transposition system. Using the partial-purified CTnDOT Int protein, an in vitro integration system was developed and a host factor(s) from Bacteroides cell extract was shown to be important for integration. …
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Functional DNA repair capacity assays : a focus on base excision repair
… prevent disease in a personalized manner. Base Excision Repair (BER) is known for the recognition and repair of endogenous and exogenous mutagenic non-helix-distorting lesions produced by DNA base alkylation, deamination and oxidation. BER is initiated by the action of one of eleven DNA …
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Replication-associated base excision repair Of oxidized bases in the mammalian genome
… breaks) are repaired via the DNA base excision repair (BER) pathway. Four mammalian DNA glycosylases, namely, OGG1 and NTH1 in the Nth family, and NEIL1 and NEIL2 in the Nei family, with overlapping substrate range initiate BER by excising oxidized base lesions and cleaving the DNA …
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Biological response to 8-oxoguanine base released during DNA base excision repair
… to guanine’s susceptibility to oxidation. A base excision repair pathway initiated by 8-oxoguanine DNA glycosylase (OGG1) excises 8-oxo-Gua lesions from nuclear and mitochondrial DNA, releasing the free oxidized base. It is well-established that failure to repair 8-oxo-Gua can result in …
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비인강암 환자에서 Excision Repair Cross-Complementation Group1 단백의 과발현이 예후에 미치는 영향
"ABSTRACT ⅰ TABLE OF CONTENTS iii LIST OF FIGURES v LIST OF TABLES vi Ⅰ. INTRODUCTION 1 Ⅱ. PATIENTS AND METHODS 3 A. PATIENTS 3 B. METHODS 3 1. Chemoradiotherapy 3 2. Evaluation 4 3. Immunohistochemical staining for ERCC1, TS and Bax 4 4. Statistical analysis 5 Ⅲ. RESULTS 7 1. Patients …
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Excision, transfer, and integration of the bacteroides integrative and conjugative element CTnDOT
… through a complex regulatory cascade. The excision operon is a key component of this regulation, and is involved at many different levels of the regulatory cascade. As the name implies, the expression of the excision operon promotes the excision of CTnDOT from the host chromosome. Once the …
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Nucleotide Excision Repair, Crosslink Repair and Transcriptional Function of Xpa In Human Cells
<p>Nucleotide excision repair (NER) in mammalian cells includes xeroderma pigmentosum group A protein (XPA) as a core factor. XPA and other NER proteins have been detected previously at some active promoters, and NER deficiency is reported to decrease activated transcription of selected genes. To …
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Η θέση του Complete mesocolic excision στον καρκίνο του δεξιού κόλου.(Βιβλιογραφική ανασκόπηση)
Η Πλήρης Μεσοκολική Εκτομή/Complete Mesocolic Excision (CME) έχει καθιερωθεί τα τελευταία χρόνια ως μία από τις σημαντικότερες εξελίξεις στη χειρουργική ογκολογία του δεξιού κόλου, εισάγοντας μία τεχνική που βασίζεται στην οξεία παρασκευή, το διαχωρισμό του σπλαγχνικού από το τοιχωματικό εμβρυικό …
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Identification of Novel Core and Accessory Factors Involved in Nucleotide Excision Repair in Yeast
ABSTRACT Nucleotide excision repair (NER) is a highly conserved DNA repair mechanism which deals with a wide variety of bulky, helix-distorting lesions, such as UV-induced cyclobutane pyrimidine dimers (CPDs). NER is traditionally grouped into two pathways: global genomic repair (GGR), which is …
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