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Showing 1 to 7 of 7 for “"ex vivo perfusion"”.
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Ex vivo perfusion optimization of donor liver grafts for transplantation and cell isolation
… pathologies however, that could be treated via ex vivo perfusion thereby increasing their cell yield. With the intent to translate organ recovery by perfusion into the clinic, we engineered a very simple room temperature-operated ex vivo organ perfusion system to test a rat liver model of …
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Computergesteuertes Perfusionssystem zur normothermen ex-vivo Vorbehandlung von Dünndarmtransplantaten
… liefert, stellt sich die Frage, ob eine ex-vivo Vorbehandlung des Organs zur Reduktion der Immunogenität Vorteile bietet. Für dieses Vorhaben wurde ein computergesteuertes ex-vivo Perfusionssystem entwickelt, das eine mehrstündige, normotherme Perfusion mit erythozytenhaltigen …
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Mitochondrial Metabolism in Ischaemia Reperfusion Injury
Ischaemia reperfusion (IR) injury is caused by the re-introduction of oxygenated blood flow to tissues after a period of ischaemia. It is an inevitable consequence of organ transplantation, where its severity contributes to reduced levels of graft function and survival. There are no clinically …
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Intravitalmikroskopische und immunhistochemische Untersuchungen zur Wirkung poly- und monoklonaler anti-Lymphozytenantikörper am konkordanten, xenogenen Primatenmodel
Es wurden zwei tierexperimentelle Versuchsaufbauten erarbeitet: 1.Die ex vivo perfusion isolierter Nieren von Macaca Fascicularis mit poliklonalem ATG 2.Perfusion der unteren Extremität von Macaca Fascicularis mit menschlichem Blut in einem geschlossenen Perfusionssystem Mit Hilfe der o.g. …
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Enhancing Metabolism of Donor Hearts for Cardiac Transplantation
… (static storage). A new technique (machine perfusion preservation) is under development and works by perfusing the organ with oxygenated preservation solution. This method may extend the donor ischemic interval and may permit utilization of less-than-optimal donor hearts - thus expanding the …
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Phenotypic and Metabolic Profiling of Biological Samples in Near Real-Time Using Raman Spectroscopy
… tissues and organs. This dissertation will show exclusively the application of the Raman spectroscopy phenotypic profiling method to; (i) microbial toxicity, (ii) ex-vivo organ perfusion, and (iii) subcellular location targeting. Real-time analytical methods for monitoring living biological …
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OXYGEN DELIVERY AND CONSUMPTION DURING HYPOTHERMIC OXYGENATED MACHINE PERFUSION AND THEIR IMPACT ON POST-LIVER TRANSPLANT OUTCOME.
… garantire un’adeguata ossigenazione durante la perfusione ipotermica epatica ossigenata con macchina (HOPE), studi recenti hanno evidenziato come l’aumento della produzione di anidride carbonica (CO2) sia associato a un maggior danno del graft. Obiettivo di questo studio è analizzare la …