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Showing 1 to 17 of 17 for “"evolutionary genomics"”.
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Comparative and Evolutionary genomics of Nucleocytoviricota
… I address this gap by performing comparative genomics and phylogenetic analysis to explore the genomics and evolutionary dynamics of giant viruses. In Chapter 1, I provide a literature review on giant viruses, their history, and their evolutionary links with eukaryotes. This chapter …
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Evolutionary Genomics of Populus trichocarpa (Western Poplar)
… these forces is a central problem in population genomics. The overall goal of this study is to characterize the relative effects of demography and selection in the genome of Populus trichocarpa, a riparian deciduous tree species of North America. Specifically, I used a variety of methods to …
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Evolutionary Genomics of the Trans-Atlantic Slave Trade
The Trans-Atlantic Slave Trade is a remarkable large-scale migration in the human history. On several occasions between the 16th and 19th century, millions of African men, women, and children were purchased from African traders and some abducted for slavery by the Europeans, for forced labour in …
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Using Evolutionary Genomics to Elucidate Parasite Biology and Host-Pathogen Interactions
… gene transfer and gene duplication as sources of evolutionary novelty . Genomic-scale phylogenetic tree comparison identifies surprisingly extensive lateral gene transfer (LGT), including plant-like genes presumably acquired from the algal source of the apicomplexan plastid (apicoplast), and …
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The evolutionary genomics of CTCF binding and functional signatures in mouse.
… Despite significant progress in the field of genomics and the rapid progress in sequencing methods and the subsequent explosion of genomic data, our understanding of the role of the non- coding genetic sequence in the regulation of tissue- and species-specific gene expression is still lagging …
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Computational evolutionary genomics : phylogenomic models spanning domains, genes, individuals, and species
… to biological data to address a wide range of evolutionary questions. In phylogenetics, methods for reconstructing gene histories from sequence data have enabled researchers to better understand how evolution shapes gene content; for example, the identification of evolutionarily-related genes …
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Evolutionary Genomics of Dominant Bacterial and Archaeal Lineages in the Ocean
… still lack a comprehensive understanding of the evolutionary processes that led to the microbial diversity we see in the ocean today. In this dissertation, I apply phylogenomic and comparative genomic methods to explore the evolutionary genomics of bacterial and archaeal clades that are relevant …
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Comparative and evolutionary genomics of secondarily temperate adaptation in a non-Antarctic icefish
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01
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Evolutionary Genomics of Cystic Fibrosis and Nosocomial Pathogens of the Mycobacterium abscessus species complex
The $\textit{Mycobacterium abscessus}$ species complex (MABSC) consists of three subspecies, $\textit{M. a. abscessus}$, $\textit{M. a. massiliense}$ and $\textit{M. a. bolletii}$. All three of these subspecies are capable of causing opportunistic pulmonary and skin and soft tissue infections in …
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An evolutionary genomics approach towards analysis of genes implicated in transmission of trypanosomes between tsetse fly and mammalian host
Human African trypanosomiasis is the world’s third most important parasitic disease affecting human health after malaria and schistosomiaisis. The world health organization estimates approximately 60 million people at risk in sub-Saharan Africa and up to 50,000 deaths per year caused by …
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Invasion genomics, adaptive evolution, and transcriptional plasticity of Anopheles stephensi in Ethiopia and Yemen : implications for malaria transmission and control.
… and Plasmodium falciparum, highlighting evolutionary feedbacks within the transmission system. High-resolution whole-genome sequencing resolves population structure, connectivity, and recent demographic history, and identifies loci under positive selection associated with insecticide …
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Investigating the role of demography and selection in genome scale patterns of common and rare variant diversity in humans
… (WGS) data has reshaped the field of human evolutionary genomics. However, many earlier sequencing projects like the HapMap and 1000 Genomes panels focussed on a limited set of populations. Therefore, more research has been required to better characterise genetic diversity in understudied …
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Adaptation and hybridization in Helicoverpa crop pests
… taxa, producing ‘experiments in evolution’. Evolutionary genetics can be used to study invasive species and inform their management. In this thesis I focus on noctuid crop pests in the genus Helicoverpa, which are among the most economically significant agricultural pests in the world. …
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New insights into cis-regulatory module evolution using in-silico evolutionary simulations
Item withdrawn by Laura Spradlin (lspradl2@illinois.edu) on 2014-11-19T15:21:57Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 1 Duque_Thyago.pdf: 5943420 bytes, checksum: 521fa3adb99bf40510252651c6b1dcca (MD5)
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Comparative and Epidemiological Genomics of Human Malaria Parasites
Following both significant advances and setbacks in the past decades of fighting malaria, the end goal of malaria elimination is now once again within sight. However, this endgame may prove the most challenging yet, as there are still significant gaps in our understanding of human malaria more …
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A SURVEY OF THE COMMON LOON (Gavia immer) GENOME REVEALS PATTERNS OF NATURAL SELECTION
… Sequencing technology, comparative genomics has become a viable method for studying the adaptation of species to their environment at the genome level. I investigated this in common loons (<em>Gavia immer</em>)—for which molecular adaptation has not been characterized—by finding …
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Developmental Basis of Wing Pattern Diversity in Heliconius Butterflies
A major challenge to evolutionary developmental biology is to understand the how modifications to gene regulatory networks can lead to biological diversity. Heliconius butterfly wing patterns provide an excellent example of this diversity. In particular, the species H. melpomene and H. erato …