Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"evolutionary contingency"”.
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A Study of Evolutionary Contingency: Characterisation, Mechanisms, and Evidence
This thesis focuses on three aspects of evolutionary contingency: (i) the characterisation of evolutionary contingency, (ii) the mechanisms of evolutionary contingency, and (iii) the evidence for and against evolutionary contingency. Part I of the thesis, which focuses on characterisation, …
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Molecular basis of the evolution of new protein functions: Kemp elimination and phosphoryl transfer reactions
… of single amino acid mutations, typical of an evolutionary trajectory, can result in dramatic changes in catalytic activity, specificity and protein solubility. Various strategies were employed to achieve this aim, including analysis of existing literature concerning the various models and …
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Molecular basis of the evolution of new protein functions: Kemp elimination and phosphoryl transfer reactions
… of single amino acid mutations, typical of an evolutionary trajectory, can result in dramatic changes in catalytic activity, specificity and protein solubility. Various strategies were employed to achieve this aim, including analysis of existing literature concerning the various models and …
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The legacy of macroevolution: understanding and predicting evolutionary responses to novel environments
… Two factors that play an important role are evolutionary constraints and contingencies. Evolutionary constraints are limitations on how species can adapt and change imposed by past evolutionary history, which could be driven by genetic, developmental, or functional variation. Evolutionary …
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Universal Biology
<p>Our only example of life is that of Earth- which is a single lineage. We know very little about what life would look like if we found evidence of a second origin. Yet there are some universal features of geometry, mechanics, and chemistry that have predictable biological consequences. The …