Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 48 for “"evolutionary analysis"”.
-
Evolutionary analysis of animal microRNAs
… are known to be highly conserved, across long evolutionary distances, many found in co-transcribed clusters across the genome. While these phenomena have been previously reported, a large-scale analysis of evolutionary patterns was still lacking. Furthermore, the rate at which new relevant data …
-
Evolutionary Analysis of Large-Scale Genomic Changes
<p>Comparative genomics reveals differences in gene order among species. In the genomes, genes are rearranged through inversion, transposition, translocation, and chromosome fission and fusion. Using gene order as a phylogenetic character has the potential to resolve previously unresolved species …
-
Evolutionary analysis in PPI networks and applications
Contains fulltext : 94194.pdf (Publisher’s version ) (Open Access)
-
Structural and Evolutionary Analysis of Developer Networks
… systems. We apply methodology from network analysis and machine learning to identify developer communities automatically. To evaluate our approach, we analyze ten open-source projects with complex and active histories, written in various programming languages. By surveying 53 open-source …
-
Evolutionary analysis of Suidae TLR signaling pathway
… their wild relatives) has diverged over extended evolutionary periods in diverse environments, suggesting that adaptation in response to endemic infectious agents may have occurred. It is therefore expected that the TLR signaling pathway might have played a crucial role in the survival of members …
-
Molecular evolutionary analysis of the American pika (Ochotona princeps)
<p>American pika (<em>Ochotona princeps</em>) are small winter-active mammals inhabiting alpine environments. As the American pika occupies a niche characterized by hypoxia, these animals are an excellent system to use for detecting genetic changes associated with adaptation to these conditions. …
-
Developmental and evolutionary analysis of betaine homocysteine methyltransferase genes
… other on the same chromosome, and to study the evolutionary relationship between them, all the available sequences from 37 species of deuterostomes were analyzed. Unlike BHMT, the BHMT-2 gene is not found in sea urchins, amphibians, reptiles and birds, indicating it was derived from BHMT …
-
Evolutionary analysis of mammalian genomes and associations to human disease
… of species differences. The genome scan analysis spurred an in*depth evolutionary analysis of the nuclear receptors, a family of transcription factors. 12 of the 48 nuclear receptors were found to be under positive selection in mammalia. The androgen receptor was found to have undergone …
-
Functional and evolutionary analysis of sugar transporters in Kluyveromyces marxianus
… that accounts for these differences, a detailed analysis of lactose utilisation was performed. The K. marxianus genome was found to encode four copies of the lactose permease (LAC12) gene, which are present in both good and poor lactose utilising strains. To determine if these genes were …
-
Evolutionary Analysis of Acetylcholine Receptors Type of Ligand-Gated Ion Channels
"In this thesis I have reconstructed the evolutionary history in animals where I focused on analyzing the complete genomes of seven widely different animals. My strategy of using complete genomes is based on ""absence of evidence is evidence of absence"". Of course there are gaps in the genetic …
-
Probabilistic Model-Based Approach to Evolutionary Analysis of Non-Coding Sequences
… bioinformatics tools that aid the comparison and analysis of genome sequences. Here, we propose and develop computational tools to evolutionarily analyze non-coding sequences, which are based on probabilistic models of sequence evolution. We present a probabilistic framework for finding the …
-
Molecular and evolutionary analysis of a gene conserved in most Orthopoxviruses
… the divergence occurred recently. Phylogenetic analysis, by the neighbour-joining method, was undertaken on the corresponding DNA sequences from variola (2 strains), monkeypox (6 strains), vaccinia (1 strain + 2 published sequences), cowpox (2 strains), taterapox, camel pox and ectromelia …
-
Evolutionary analysis and functional characterization of the forkhead transcription factor FoxG1
Forhead box G1 (FoxG1) is a winged-helix transcription factor that plays a crucial role in the development of the telecephalon, the most rostral region of the brain Here, FoxG1 acts as a transcriptional repressor and maintains the population of cortical progenitor cells by promoting their …
-
Functional Characterization and Evolutionary Analysis of Lepidopteran Cytochrome P450 Genes Involved in Plant -Insect Interaction
… of these enzymes. Here we demonstrate, using evolutionary, functional and structural methodologies to investigate the significance of positive selection for diversification of the lepidopteran CYP6B subfamily, that positive selection is the dominant force driving diversification of newly …
-
The Discovery and Evolutionary Analysis of Divergent Homologs Involved in Cattle Immune and Reproductive Biology
… identified using a subtractive bioinformatic analysis of 12,614 cattle placenta ESTs followed by comparative, evolutionary and gene expression studies. Eight have not been identified previously. These were named: CSSMST1, CIST1, HAVCRNDP, PRP8, PRP9, PRP11, SECTM1A and SECTM1B. Nucleotide …
-
Merging decision support and expert system technologies : an evolutionary analysis and proposals for an architectural framework
The fact that competence in decision-making differentiates the effective manager from the ineffective manager <Harrison.1981: l>J makes decision-making one of management's printiple concerns <Uliana.1986:1). The implication of this for DSS research is that means have to be sought that could …
-
Molecular, Biochemical, and Evolutionary Analysis of Single-Stranded Dna-Binding Proteins From the Mesophilic Archaeon Methanosarcina Acetivorans
… proteins. Based on these results we proposed evolutionary models to explain how intramolecular and intermolecular homologous recombination processes might have led to domain deletion and gene fusion to generate the diverse RPA homologs found in extant euryarchaeotes."
-
The Origins of Terpene Infochemicals in Insects: Identification and Evolutionary Analysis of Terpene Synthases in Diverse Lineages
… of major insect lineages. First, I investigated evolutionary and functional relationships of TPS enzymes with roles in pheromone biosynthesis in pentatomids (stink bugs) including the invasive and economically critical pests Nezara viridula (Southern green stink bug) and Halyomorpha halys (brown …
-
The Development and Application of Methods to Study the Evolution of Specificity, Allostery, and RNA -Protein Interactions in Translation
… the sequence QR algorithm to generate complete evolutionary profiles that represent the topology of the molecular phylogenetic tree of the homologous group. These biasless profiles were used to identify a putative class II cysteinyl-tRNA synthetase (CysRS) in several archaea that eluded previous …
Page 1 of 3