Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"etanercept"”.
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Análisis costo versus efectividad del Etanercept, Infliximab y Adalimumab, en pacientes con artritis reumatoide refractaria
… Empresa Promotora de Salud (EPS) en Colombia: el Etanercept, Infliximab y Adalimumab. Dicho análisis se realizará de manera cuantitativa, para poder determinar cuál de ellos es la primera opción más costo-efectiva.
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Optimización del rango terapéutico de niveles de fármaco y anti-fármaco de terapia biológica anti-tnf-alfa en artritis reumatoide
… anti-TNF-alfa (infliximab, adalimumab y etanercept) ha mejorado el pronóstico, pero su eficacia puede verse afectada por la formación de anticuerpos antifármaco y estar condicionada por la variabilidad en niveles de fármaco. Este estudio se centra en la monitorización terapéutica de …
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Dendritic Cells in Normal and Inflamed Human Skin
… patients with the TNF neutralizing antibody etanercept not only inhibited dendritic cells as expected, but also had inhibitory effects on a newly appreciated type of T cell – Th17 cells. Etanercept reduced inflammatory DC products that drive Th17 cell proliferation (IL-23) as well as Th17 …
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The conclusion of a biologic's lifecycle : manufacturing sourcing strategies on the eve of follow-on biologics
… bulk drug substance (BDS) for Enbrel® (etanercept), which blocks the action of one's immune system, helping to treat immune diseases, such as rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and psoriasis. A productivity process improvement is currently being …
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Measure for measure. Outcome assessment of arthritis treatment in clinical practice
… and SpA commencing treatment with adalimumab, etanercept or infliximab, date of treatment start and stop, core set variables and EQ-5D were recorded, and various activity indices, responses and EQ-5D utility were calculated. Descriptive statistics and completer analysis were used. The NNQ was …
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Immunodulation of inflammation in a murine pnemococcal sepsis model
… after antibiotic treatment prompted our study of Etanercept (a tumor necrosis factor alpha neutralizing agent) as an adjunctive therapy against systemic S. pneumoniae. TNF is a major therapeutic target since it appears early and is related to disease severity. Balb/c mice were inoculated …
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Οι λοιμώξεις σε ασθενείς με ρευματοειδή αρθρίτιδα: μία βιβλιογραφική ανασκόπηση
… κορτικοστεροειδών ακόμη και χαμηλής δόσης. Το etanercept πιθανόν είναι ασφαλέστερο φάρμακο ως προς τον κίνδυνο εμφάνισης λοιμώξεων, συγκριτικά με τα υπόλοιπα τις κατηγορίας του. Η ταυτόχρονη λήψη δύο βιολογικών παραγόντων δεν αυξάνει στατιστικά σημαντικά τον κίνδυνο λοιμώξεων. Όσον αφορά την …
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Anti-TNF treatment of chronic arthritis in clinical practice. New assessment method and predictors of efficacy and tolerability.
… termination was higher in infliximab compared to etanercept treated patients. Also, regression analysis showed that patients with higher baseline CRP-levels and concomitant MTX treatment had better overall treatment continuation. Good response to anti-TNF therapy in RA was associated with …
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TARGETING COCHLEAR INFLAMMATION FOR THE TREATMENT OF CISPLATIN OTOTOXICITY
… of TNF-α by trans-tympanic administration of etanercept, a clinically used TNF-α antagonist, protects against OHC damage and cisplatin-induced hearing loss. These data suggest that targeting STAT1 or the inflammatory genes it regulates could serve as useful strategies for preventing …
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Treatment of arthritis with tumour necrosis factor antagonists. Clinical, immunological and biochemical aspects
… in RA patients treated with infliximab and etanercept during the initial 6 months of treatment. Serum COMP levels decreased in patients with and without a clinical response, suggesting a damage retarding effect of TNF antagonist treatment. Altogether, 149 patients with RA participated in …