Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"esophagitis"”.
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The Pathophysiology of Eosinophilic Esophagitis: Altered Mechanisms of Antigen Detection in the Esophagus
… has emerged, which is now known as eosinophilic esophagitis (EoE). Incomplete knowledge regarding the pathogenesis of EoE has limited treatment options. EoE is known to be a Th2-type immune-mediated disorder. Based on previous studies in both patients and experimental models, it is possible that …
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Investigation of Radiation Injury In The Esophagus From Definitive Chemoradiation Therapy Using Novel Imaging Biomarkers
… of non-small cell lung cancer (NSCLC). Radiation esophagitis is an acute normal tissue toxicity that negatively affects treatment efficacy by limiting dose and potentially interrupting radiation therapy. Clinical quantification of this toxicity is typically achieved by utilizing physician grading …
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Studies of in situ nitrosative stress following nitrate ingestion in the human upper gastrointestinal tract
… may be harmful to patients with erosive esophagitis whose epithelium will be more sensitive to chemical mutagenesis.
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Protonų siurblio inhibitorių suvartojimo tyrimas Lietuvoje 2022 metais /
… in Lithuania in 2022 were: K21.9: GERD without esophagitis K21.0: GERD with esophagitis The highest PPI consumption was in Rokiškis district municipality (15.15 DDD/1000 inhabitants) and the lowest in Plungė district municipality (4.66 DDD/1000 inhabitants). The greatest disparities in PPI …
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Control of inflammation, helper T cell responses and regulatory T cell function by Bcl6
… and also in human patients with eosinophilic esophagitis and asthma. Thus, miR-21 is a clinically relevant biomarker for Th2-type pathologies. Our results define a key function for Bcl6 in repressing Gata3 function and miR-21 expression in Tregs, and provide greater understanding of the …
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The Impact of Vitamin D on the Epidemiology, Pathogenesis, and Treatment of Esophageal Adenocarcinoma
… inhibit the Th1 response associated with reflux esophagitis while fostering the Th2 response associated with Barrett’s esophagus. Other immune cells including macrophages, dendritic cells, Th17 cells, and Tregs may be influential to the development or prevention of EAC, but their specific roles …
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ADENOCARCINOMA DE GLÂNDULA SUBMUCOSA NO ESÔFAGO EM UM CÃO: RELATO DE CASO
… from highly malignant neoplasms to "persistent esophagitis" that may be chronic and disabling or merely an occasional nuisance. The present work aims to report the case of a dog diagnosed with Adenocarcinoma of the submucosal gland of the esophagus, attended at “MinhaCriaVeterinários” clinic in …
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D-arabinitol in the diagnosis of invasive candidiasis
… were not detected in five patients with Candida esophagitis. Clinical usage of DA/LA ratio in urine was studied iat the pediatric oncology unit (POU) and at the neonatal intensive care unit (NICU) in Lund. Screening of neutropenic children with cancer at the POU was found to decrease the number …
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Noncanonical NF-KB in Gastrointestinal Disease
… namely a novel model of the disease eosinophilic esophagitis. Our studies revealed that loss of NF-KB-inducing kinase (NIK), the bottleneck molecule in noncanonical NF-KB signaling, results in targeted esophageal inflammation, remodeling, and gene expression changes that are comparable to the …
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Dysregulation of Noncanonical NF-κB Signaling in Gastrointestinal Diseases
… diseases of the gut, including Eosinophilic Esophagitis (upper GI tract), Celiac Disease/Non-Celiac Gluten Sensitivities (small intestine), Inflammatory Bowel Disease (entire intestine/large intestine), and an inflammatory subtype of colorectal cancer being Colitis-Associated Colorectal …
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Integrated, single-cell analysis of transcriptional phenotype and clonotypic identity
… patients with the allergic disease eosinophilic esophagitis (EoE) with scRNA-seq. We identify a clonally expanded, pathogenic effector Th2 (peTH2) cell phenotype that is associated with EoE. This phenotype demonstrates features of an antigen-specific T cell response, including convergence of TCR …
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Investigating mitochondria alterations in esophageal pathologies
… in esophageal diseases, including eosinophilic esophagitis (EoE), an emerging food allergy and immune-mediated inflammatory disorder, and esophageal squamous cell carcinoma (ESCC), an aggressive malignancy associated with poor patient outcomes. Roles for esophageal epithelial cells in the …