Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"erythritol"”.
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Erythritol metabolism in a dome mutant of Schizophyllum commune
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Investigating Rhizobium Leguminosarum Metabolism and Rhizosphere Colonization Using High-Throughput Genomics and Erythritol Enrichments
… environmentally harmful nitrogen fertilizers. Erythritol is exudated from legume roots, and is catabolized by Rhizobiaceae genera. The goal of the thesis is to explore how erythritol influences community composition, and to discover novel genes influenced by erythritol catabolism in Rhizobium …
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Control of Substrate Supply to the Chloroplast 2-C-methyl-D-erythritol-4-phosphate Pathway
The chloroplast 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway supplies precursors for plastidic terpenoid biosynthesis, making it a focal point for manipulating terpenoid production in plants. The MEP pathway generates the universal terpenoid intermediates isopentenyl and dimethylallyl …
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Role of entF Gene in Iron Acquisition by Brucella abortus 2308
… affects the ability of pathogen to metabolize erythritol, replicate in trophoblast cells and cause abortion in pregnant ruminant host. The entF gene has been implicated in the unresolved pathway allowing brucebactin biosynthesis in Brucella. The research effort presented in this thesis tries to …
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Investigating pathogen 4Fe-4S protein targets and cancer chemotherapies with bisphosphonate/diphosphate inhibitors
… main areas of focus are inhibition of the Methyl Erythritol Phosphate (MEP; non-mevalonate pathway) pathway in bacterial and parasitic human pathogens and inhibition of isoprenoid synthases in human cancers. For the development of antibacterials and antiparasitics, this research investigates the …
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Evaluation of dental hygiene prophylaxis systems on dental implants: randomized clinical trial of changes in oral health status
… health. The two approaches compared were erythritol-based air polishing and ultrasonic instrumentation with PEEK-coated tips. A total of 120 patients with at least one implant-supported crown—restored with feldspathic ceramic, zirconia, or lithium disilicate—were recruited and randomly …
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Thermal Performance Modeling of a Novel Dual-PCM Evacuated U-Tube Solar Collector
… PCM as a HTF, in which HITEC molten salt and erythritol (C4H10O4) was chosen. This study also analyzes PCM doped with nanoparticles to be used as HTFs directly integrated in the dual-PCM EUTC. Preliminary analysis showed that erythritol would be a better combination as a HTF in moderating …
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Auswirkungen der Deletion membranständiger Dehydrogenasen auf Gluconobacter oxydans DSM 7145
… Anzucht von G. oxydans DSM 7145 auf VM + meso-Erythritol zeigte, dass meso-Erythritol zunächst nahezu quantitativ zu L-Erythrulose oxidiert wird, in einer zweiten Wachstumsphase jedoch eine Abnahme der L-Erythrulose-Konzentration im Kulturüberstand zu beobachten war, die mit einer Akkumulation …
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Possible carriers in mouse erythrocytes
… such as glycerol, ethylene glycol and erythritol would penetrate less rapidly than lipid-soluble non-electrolytes. It was thought that the rate of penetration of water-soluble non-electrolytes was inversely proportional to their molecular size and the penetration of lipid-soluble …
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Physical, Behavioral, Psychological, And Metabolomic Predictors Of Weight And Adiposity Change In Young Adults
… showed baseline plasma concentrations of meso-erythritol and fructose, two dietary sweeteners, were respectively 15- and 2-fold greater among participants who subsequently experienced increased central adiposity, compared to participants who maintained a stable adiposity phenotype. Conclusions: …
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Coprocessing via spray drying as a formulation platform to improve the compactability of various drugs
… van een geneesmiddel met koolhydraten (erythritol, maltodextrine, mannitol), superdesintegrant (crospovidone), glijmiddel (colloïdaal silicium dioxide) en surfactant (polyoxyethyleen 20 sorbitan monooleaat) verbeterde de produceerbaarheid, hygroscopiciteit, vloeibaarheid en …
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Structural studies to inform antimicrobial drug discovery and the basis of immunity against T6 effectors
… drug targets.<br/>The protein IspF (2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, EC: 4.6.1.12) from two pathogens (Burkholderia cenocepacia and Plasmodium falciparum) has been investigated. IspF is an enzyme of isoprenoid-precursor biosynthesis and is considered to be a potential drug …
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Glycerol permeability in two species of Peromyscus
… of the erythrocytes of rat and mouse to erythritol, mannitol, glycerol, and thiourea. Rat erythrocytes were more permeable to glycerol than to thiourea, whereas the reverse was true for mouse erythrocytes. Mouse erythrocytes also displayed a high degree of permeability to erythritol. …
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Cold-acclimation of the wood cockroach <i>Cryptocercus punctulatus</i> (Scudder) (Dictyoptera: Cryptocercidae)
… They are: glycerol, sorbitol, mannitol, erythritol, and threitol. There is one report of the occurrence of an unidentified 5-carbon polyol, possibly either arabitol or ribitol from whole body extracts of winter-acclimated collembolans. This thesis documents the occurrence of ribitol in …
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The relevance of bacterial isoprenoid biosynthetic pathways for host-microbe interactions
… pathways (Mevalonate (MVAL) and 2-C-methyl-D-erythritol 4-phosphate (MEP)) for host-microbe interactions. We determined a significant reduction in microbial diversity in the murine gut microbiota (by next generation sequencing) following oral administration of a common anti-cholesterol drug …
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The Synthetic Biology of N2-Fixing Cyanobacteria for Photosynthetic Terpenoid Production
… chemical. In cyanobacteria, the 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway is responsible for building essential metabolites involved in photosynthesis, as well as precursors for terpenoid biosynthesis. This dissertation encompasses research focused on redirecting MEP flux in the …
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Approaches to understanding diversity in rubber and carotenoid synthesis in <i>Hevea brasiliensis </i>latex
… (MVA) pathway and the plastidic methyl erythritol phosphate pathway (MEP). This study utilised two rubber tree clones (RRIM600 and PB235) that show visibly contrasting levels of yellow carotenoids for the measurement of latex isoprenoids (carotenoids, rubber and isoprenoid intermediates) …
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Design and development of polymeric nanoparticles by continuous manufacture using twin screw extrusion
… carriers, xylitol (XYL), sorbitol (SORB) and erythritol (ERY), was assessed in addition to predicted required shear rates in order to produce homogenous mixtures of nanoparticles. Additionally, the ability to scale up the process was investigated with promising results. It was shown that the …
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Experimental investigation of U-Pipe evacuated tube solar collector: thermal performance enhancement methodology
… (HITEC), tritriacontane paraffin wax (PCM72) and erythritol. In order to overcome the low thermal conductivity and further enhance specific heat capacity, various weight concentrations of multi-walled carbon nanotubes (MWCNT) are added. Additionally, to insure even distribution of MWCNT and …
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