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Showing 1 to 2 of 2 for “"eptifibatide"”.
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Development and experimental validation of a novel arterial thrombosis-on-a-chip microfluidic device
… I tested the approved anti-platelet drug, eptifibatide in both quenched and unquenched devices. In quenched devices, I measured a significant difference in the ‘time to occlude’ in treated devices compared to control conditions. These results were not replicated in unquenched devices, …
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The Tetraspanin CD9 Localizes to Platelet-Platelet Contacts and Regulates Thrombus Stability
… inhibit, platelet disaggregation induced by eptifibatide. Interestingly, CD9 perturbation did not alter platelet-mediated clot retraction of platelets in PRP (Platelet rich plasma). In response to CD9 alteration by mFab7, both increased fibrinogen binding and platelet activation (as evidenced …