Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"epoxyeicosatrienoic acid"”.
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Molecular Mechanisms of Itch Sensations
… application of endogenous TRPV4 agonist, 5, 6-epoxyeicosatrienoic acid: 5, 6-EET), caused scratching responses that were significantly attenuated in TRPV4-/- mice. Interestingly, TRPV4-/- mice had reduced scratching responses in ACD mice model without affecting on skin inflammation. TRPV4 …
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Cytochrome P450 2J2 mediated metabolism of omega-6 and omega-3 endocannabinoids
… mediates the metabolism of polyunsaturated fatty acids into oxygenated bioactive metabolites. This enzyme is most well-known for the conversion of arachidonic acid into epoxyeicosatrienoic acids (EETs) regioisomers, 14,15-, 11,12-, 8,9-, and 5,6-EET that mediate vasodilatory, pro-angiogenic and …
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The influence of acute, chronic and lifelong hypoxia on the functional and structural integrity of the neurovascular unit
… hydrolase L1 [UCH-L1], glial fibrillary acidic protein [GFAP], neurofilament light-chain [NF-L] and total-tau [T-Tau] determined via automated clinical grade ELISA and Single Molecule Array technology). Cardiopulmonary variables included mean arterial pressure (MAP), heart rate (HR), …