Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"epoxyeicosatetraenoic acid"”.
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Studies Toward the Syntheses of Antiarrythmic, Anti-Virulence, and Anticancer Small Molecules
… of antiarrythmic analogs of 17(R),18(S)-epoxyeicosatetraenoic acid for the treatment of atrial fibrillation, b) the development of potent inhibitors of QseC mediated virulence gene expression, and c) studies toward a biomimetic total synthesis of nigricanoside A. Antiarrhythmic analogs of …
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Cytochrome P450 2J2 mediated metabolism of omega-6 and omega-3 endocannabinoids
… mediates the metabolism of polyunsaturated fatty acids into oxygenated bioactive metabolites. This enzyme is most well-known for the conversion of arachidonic acid into epoxyeicosatrienoic acids (EETs) regioisomers, 14,15-, 11,12-, 8,9-, and 5,6-EET that mediate vasodilatory, pro-angiogenic and …