Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"epitope vaccine"”.
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Refinement of the Computational Vaccine Optimization Framework (OptiVax) through the development and analysis of a better algorithm for vaccine design choice
… of the maximum 𝑛- times coverage problem to epitope vaccine design (OptiVax) and compare various vaccine designs both found in the literature and produced by the three aforementioned algorithms.
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Development of a Neoepitope Prioritization Platform to Identify Immunogenic Neoantigens from Oncogenic FGFR3-TACC3 Fusion in Glioblastoma
… fusion detection, fusion reconstruction, neoepitope prediction, experimental validation, and safety filtering. This platform enables both fusion-centric and peptide-centric strategies for multi-epitope vaccine design and TCR-based therapies, while introducing data-driven refinement of …
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Characterization of the alfalfa mosaic virus as expression, presentation, delivery and screening system for potential epitopes derived from the respiratory syncytial virus fusion protein
… the last decade and consequently their use as vaccines has become an increasingly viable proposition. In this study it was investigated if Alfalfa mosaic virus could be used to present (i) an RSV-F-derived peptide library, (ii) phage-selected mimics and (iii) anti-viral peptide fusion …
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Harnessing In Silico platform for Vaccine Discovery, Disease Modeling, and Immunotoxicity Prediction in Pandemic and Emergency Scenarios
Il mondo moderno affronta sfide senza precedenti derivanti da pandemie ed emergenze, richiedendo soluzioni innovative per una gestione efficace. Questa tesi affronta problematiche di salute globale utilizzando strumenti computazionali avanzati per la scoperta di vaccini, la modellazione delle …