Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"epitope masking"”.
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Immunologic Memory to Polysaccharide Antigens
… via a mechanism that does not depend on epitope masking or involve known Fcγ receptors.</p>
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Investigating the Effect of Antibody-Mediated Feedback on Ongoing Germinal Center Responses
… B cell receptor specificities to non-overlapping epitopes on the same antigen, allowing us to distinguish between epitope-specific and epitope-non-specific effects of secreted antibody. In addition, we have genetically engineered a Blimp-1-DTR mouse that allows for temporally controlled ablation …
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Interplay between Extra-Germinal Center expansion of memory B cells and affinity maturation during the humoral recall response
… is pertinent to effectively targeting conserved epitopes, amplifying antibody responses, and providing broad protection against mutable variant pathogens. This thesis uses a variety of computational models describing the GC and EGC processes, aiming to enhance our understanding of the generation …