Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"epithelial model"”.
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Studies of in situ nitrosative stress following nitrate ingestion in the human upper gastrointestinal tract
… We utilised a specialised silicone tube as an epithelial model, inserting it into the upper gastro-intestinal tract of humans. Healthy volunteers were studied with and without ingestion of 15N enriched nitrate and Barrett’s oesophagus patients with and without stimulation of reflux. In …
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MUCIN-MEDIATED AND INTERFERON-DRIVEN DEFENSE MECHANISMS AGAINST INFLUENZA VIRUS INFECTION IN HUMAN AIRWAY EPITHELIUM
… proteins termed mucins. Additionally, underlying epithelial cells produce interferons upon virus detection that promote the establishment of a local antiviral state through autocrine and paracrine signaling. However, despite these protective measures, IAV continues to cause significant annual …
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In vitro model of periodontal epithelium
To develop a model for junctional epithelium, porcine periodontal ligament epithelial cells (PLE cells) were cultured from the epithelial rests of Malassez. The obtained epithelial cell lines were grown on a porous membrane that allows a good cell adhesion and access of the nutrients from both …
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Novel therapies for cancer treatment : designing high affinity selective ligands against SIRT1 enzyme
… lines, it has been found that the lung cancer epithelial model A549, the colorectal adenocarcinoma model Caco-2, the liver hepatic model HepG2 were very sensitive with an IC50 (0.32, 0.67, 0.2μM) respectively. Both breast cancer models (MCF-7 and MDA-MB-468) were highly sensitive with an IC50 …
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Nebulizer facilitated molding of freeform 3D printed sacrificial scaffolds for breast tumor microenvironment tissue engineering
… geometries in tissue engineered organs and models. Luminal structures are necessary for providing function in epithelial tissues including breast ducts, lungs, liver, and kidney. Cylindrical vessels are also necessary for expanding the size of model organs, delivering glucose and oxygen …
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The role of probiotics, prebiotics, and human milk oligosaccharides in infant formulae
… in a second trial utilizing the a similar model as that discussed above (Holscher et al., 2012b). Prebiotics are selectively fermented ingredients that result in specific changes, in the composition and/or activity of the GI microbiota, thus conferring benefit(s) to the host (Gibson et al., …