Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"epigenetic memory"”.
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Epigenetic Memory of Mouse Intestinal Inflammation
… from damage, suggesting the possibility of memory. Such epigenetic memory may confer some adaptive resiliency to subsequent damage.
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The Role of DNA Methylation in the Regulation of Skeletal Muscle Atrophy, Hypertrophy and Epigenetic ‘Memory’
… skeletal muscle, remain elusive. In this regard, epigenetics, referring to alterations in gene expression via structural modifications of DNA without fundamental alterations of the DNA code, have recently become a promising area of research, specifically for its role in modulating genetic …
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Fasting alters histone methylation in paraventricular nucleus of chick through regulating of polycomb repressive complex 2
… if not all, related to the dynamic reversible epigenetic imprints left on the histones [6,7,8], especially during the prenatal and postpartum period [9]. Histones are highly dynamic and responsive towards environmental stress [10,11]. Through covalent modification of the histone tail, histones …
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The Skin Remembers: Epigenetic Memories of Inflammation Past
… an adaptive mechanism whereby EpSCs retain an epigenetic memory of prior inflammatory exposure that endows them with enhanced sensitivity and responsiveness to subsequent tissue damage. During secondary injury, inflammatory memory is mediated by cytosolic dsDNA sensor and activator of the …
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Establishment of the epigenetic landscape in mammalian embryonic stem cells
… development. Deciphering the details of such epigenetic phenomena has the potential to enrich both stem cell biology and therapeutics, as well as offer insight into various pathologies. While the enzymatic machinery responsible for these transitions is well known, it is their localization to …
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Scalable Methods for In Situ Genomics
… chromatin domains in zygotes, and uncover epigenetic memory of global chromosome positioning within individual embryos. We conclude with a discussion of IGS scaling properties, by which we can anticipate many-fold future improvements in yield and resolution. We anticipate IGS and related …
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Large replisome-dependent heterochromatic domains defining the transgenerational regulatory landscape
… in the puzzle to understanding transgenerational epigenetic inheritance (TEI) is a mechanism that allows epigenetic information to be stored and propagated, not only from one generation to the next, but across cell division. Histone modifications, along with small RNAs (sRNA) and DNA methylation, …
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Generation of induced progenitor-like (iPL) cells using interrupted reprogramming
… Furthermore, harnessing the residual epigenetic “memory” and the plasticity existing in the early stage of the reprogramming process, interrupted reprogramming is able to rejuvenate aged endogenous progenitor AEC-II cells to a youthful state by ameliorating multiple hallmarks of aging, …
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Theoretical and Computational Studies on the Dynamics and Regulation of Cell Phenotypic Transitions
… The regulation can take place at the epigenetic, transcriptional, translational, and post-translational levels to name a few. Epigenetic histone modification plays an important role in cell phenotype maintenance and transitions. However, the underlying mechanism relating dynamical …
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Between Being and Becoming: How Might Surprise Create New Meaning Co-ontologically in the Design Production and Reception of Immersive-Media?
… any existing temporal, cultural relation in memory to the triggering object or entity, enabling a remembering of a previously forgotten capability. This recollection happens in the moment of the pause, halting or break in conscious registration, when the unqualified intensity in approach …