Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"epigenetic imprinting"”.
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The Role of TCR Engagement Strength in Antitumor CD8 T Cell Exhaustion
… position- ing to dendritic cell niches and epigenetic imprinting that involves increased chromatin accessibility at Egr2 and Tcf1 target loci. Collectively, my dissertation work reveals a previously unappreciated and coun- terintuitive role of TCR stimulation in preserving Tpex and …
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Fasting alters histone methylation in paraventricular nucleus of chick through regulating of polycomb repressive complex 2
… if not all, related to the dynamic reversible epigenetic imprints left on the histones [6,7,8], especially during the prenatal and postpartum period [9]. Histones are highly dynamic and responsive towards environmental stress [10,11]. Through covalent modification of the histone tail, histones …
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Do respiratory epithelial cells ‘remember’ early life microbial exposure through epigenetic changes?
… changes in immune responses were possible due to epigenetic or metabolomic imprinting. This phenomenon was also observed in plants and invertebrates and termed ‘trained immunity’. Several cohort studies have linked severe respiratory syncytial virus (RSV) bronchiolitis in infancy with a higher …