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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"epigallocatechin gallate"”.
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Epigallocatechin Gallate in the Regulation of Insulin Secretion
… the acute and relative long-term effects of epigallocatechin gallate (EGCG) on insulin secretion and synthesis from clonal beta-cells (INS1E cells), rat islets, and human islets, using 0.1, 1, or 5 µM. We determined if EGCG decreased blood glucose in healthy rats acutely, using 50 or 150 …
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Development of a topical epigallocatechin gallate (EGCG) formulation
Epigallocatechin gallate (EGCG) is a potent polyphenoclic antioxidant extracted from green tea. Due to its antimutagenic and antitumor activities it is a promising candidate for use in topical formulations for skin cancer prevention. The overall objective of this dissertation was to develop a …
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Green tea extract and epigallocatechin gallate decrease muscle pathology and NF-κB immunostaining in regenerating muscle fibers of mdx mice
… Green tea extract and its primary polyphenol, epigallocatechin gallate, have been shown to have anti-inflammatory properties and to improve dystrophic muscle pathology. The purpose of these studies was to determine if dietary treatment with green tea extract or epigallocatechin gallate …
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A Molecular Dynamics Study on the Interaction of Tea Catechins and Theaflavins with Biological Membranes
… catechins able to penetrate beneath the surface. Epigallocatechin-gallate (EGCG) and Theaflavin-3,3'-digallate showed the strongest interaction with the lipid bilayers based on the number of hydrogen bonds formed with lipid headgroups. The simulations also provide insight into the functional …
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Overcoming the biological barriers to intravenous delivery of stem cells and drugs for the treatment of vascular-related diseases
… are devised to rapidly discharge antioxidant epigallocatechin gallate in response to elevated levels of hydrogen peroxide. The stem cells survived in sub-lethal concentrations of hydrogen peroxide and maintained their angiogenic potential in vivo. The second part of this dissertation looks at …
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Flavonoid protection of cardiac cells against ischemia-reperfusion injury
… cell death was given by catechin (44-58 %), epigallocatechin gallate (48%), proanthocyanidins (44%), and ascorbic acid (57-92%). A low concentration (10 µM) of catechin was more effective with a long-term (2 days) incubation time (64%), while a higher concentration (50 µM) could exert benefit …
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The Chemistry of Flavonoids in Model Beverages and Human Milk
… Epicatechin (63.7-828.5 nmol/L), epicatechin gallate (55.7-645.6 nmol/L), epigallocatechin gallate (215.1-2364.7 nmol/L), naringenin (64.1-722.0 nmol/L), kaempferol (7.8-71.4 nmol/L),hesperetin (74.8-1603.1 nmol/L), and quercetin (32.5-108.6 nmol/L) were present in human milk samples with high …
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PEDOT Electrodes as Redox Mediators for Determination of Antioxidants in Beverages
… the optimum conditions. Green tea, catechin and epigallocatechin gallate solutions were used as test standards for system optimization. The optimum number of preparative cycles and potential range were determined to be cycling four cycles between -300 and 1200 mV vs. Ag/AgCl. Tea and coffee are …
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Silica nanoparticles as vehicles for therapy delivery in neurological injury
… for study, a natural product in green tea, epigallocatechin gallate (EGCG), has been explored for its ability to react with acrolein, disabling its reactive capabilities. Upon demonstration of attenuating acrolein, EGCG's delivery may also be improved using the nanomedical approach. The …
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Effect of yerba mate tea caffeine and green coffee by-products on in vitro adipogenesis and lipid accumulation and their incorporation into functional beverages
… of lipid accumulation compared to SC (16.3%), epigallocatechin gallate (EGCG) (17.5%), and Orlistat (17.9%). Adipocytes treated throughout differentiation resulted in an elevated inhibitory effect, with MT (22.8 ± 2.2%) and GC1 (26.8 ± 1.8%) having similar inhibitory capacity to SC (29.3 ± …
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Role of salivary films in assessing astringent compounds
… with minimal levels, if any, of PRPs. <br/>Epigallocatechin gallate (EGCG), a polyphenol containing a galloyl ring, interacts with MUC5B to a much lower extent than with PRPs. However, this interaction is enough to alter and enhance the binding of MUC5B and other salivary proteins shown to …
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Inhibiting platelet scramblase activity
… The polyphenolic compounds tannic acid and epigallocatechin gallate (EGCG’) inhibit TMEM16F activity when over-expressed in cell lines. Both tannic acid and EGCG’ are shown to inhibit platelet scramblase activity. An empirical screen of polyphenolic compounds defined an emerging …
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Modified Green Tea Polyphenol, Palmitoyl-EGCG and Black Tea Theaflavins: Promising Natural Herpes Simplex Virus 1 and 2 Agents
… need to be developed. Green tea’s polyphenol epigallocatechin gallate (EGCG), and its modification palmitoyl-EGCG (p-EGCG), along with black tea theaflavins TF1, TF2, TF3 have been used to study their antiviral effect against HSV type 1 (HSV-1) and HSV type 2 (HSV-2). These compounds with …
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INHIBITION OF ACTIVITIES OF INDIVIDUAL SUBUNITS OF INTESTINAL MALTASE-GLUCOAMYLASE AND SUCRASE-ISOMALTASE BY DIETARY PHENOLIC COMPOUNDS FOR MODULATING GLUCOSE RELEASE AND GENE RESPONSE
… and SI. For instance, chlorogenic acid and (-)-epigallocatechin gallate (EGCG) selectively inhibited the most active starch digesting subunit, Ct-MGAM (also called glucoamylase). We additionally used rat intestinal acetone powder and human intestinal tissue to investigate the inhibitory effects …
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Anticancer Effects of Vitamin E Forms and Their Long-chain Metabolites via Modulation of Sphingolipid Metabolism
… including curcumin, resveratrol, and epigallocatechin gallate, etc. also modulated sphingolipid metabolism in cancer cells. Overall, our studies demonstrate that γTE and 13’-COOHs have potent anticancer effects by modulating enzyme activities in sphingolipid metabolism.
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A comparative study of white, black and green tea solutions as potential antiviral agents in rhesus monkey kidney cells induced with porcine rotavirus
… (-) epicatechin (EC) (4.3 - 16.5 μg/mg SE), (-)-epigallocatechin (EGC) (9.6 - 76.9 μg/mg SE), gallocatechin gallate (GCG) (15.1 - 43.6 μg/mg SE), and (-)-epigallocatechin gallate (EGCG) (48.6 - 151.0 μg/mg SE). EGCG was found to have the highest concentration in White, Black, and Green Tea …
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RegulationofGap Junction Protein,Connexins in Immortalized Human Keratinocytes Cells(HaCaTcells)
… and green tea extract epicatechin (EC) and epigallocatechin gallate(EGCG) were used for this study. These substances were first applied on the HaCaT cell line according to their concentration. After they were cultured for 24 hours, the cytotoxicity was analyzed by quantitatively assessing …
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The effects of green tea, green rooibos and their major flavonoids (EGCG and aspalathin) on testicular cell health in vitro
… Polyphenols, and especially the flavonoids: epigallocatechin gallate (EGCG, from green tea) and aspalathin (from green rooibos), are held as primarily responsible for their health benefits. These flavonoids are known antioxidants that can interact with proteins, carbohydrates and fats, making …
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Effetti del chitosano su composti polifenolici in colture cellulari di vite: aspetti molecolari e metabolici
… acids), 5 catechines (catechin, epicatechin, epigallocatechin-gallate (EGCG), epigallocatechin and epicatechin-gallate) and other 5 flavonoids (chalcon, naringenin, kaempferol, quercetin and rutin) in cells and cultural medium, were measured by HPLC-DAD analysis and total anthocyanins were …
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