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Cardiac repair post-myocardial infarction: Roles of the primary cilium and the long non-coding RNA Malat1

Blom, Jessica NThe University of Western Ontario2017

… MI pathology. We found that indeed epicardial cells are ciliated, and primary ciliary disassembly supports EMT post-MI, which enhances the contribution of epicardium-derived cells (EPDCs) to neovascularization. This reduced deleterious cardiac remodeling and preserved cardiac function. …

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