Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"ependymal cells"”.
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Neurogenesis from Neural Stem Cells, Ependymal Cells and Fibroblasts
… Stroke leads to loss of neurons and also other cells in the brain due to lack of blood supply. Currently no therapies are available to treat stroke-related disability. It has been shown that stroke leads to increased neurogenesis, birth of new neurons, within the brain. This increased …
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The role of retinoids in the regeneration of the axolotl spinal cord
… has been described in juvenile Axolotl ependymal cells. Retinoid effects may possess a significant role in the regeneration-permissive interaction of the meninges and ependyma of the Axolotl spinal cord after penetrating injury. During spinal cord regeneration in urodele amphibians, the …
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A Niche for Adult Neurogenesis: Analysis of BMP Signaling and Transcriptional Profiles of Adult Subventricular Zone Cells
… (SVZ) of the lateral ventricle wall. Neural stem cells reside in the SVZ. The SVZ cell types and molecular signals necessary for this neurogenic niche were poorly understood. Here, I first demonstrate that astrocyte-like cells in the SVZ (type B cells) can self-renew and differentiate into mature …
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The Ultrastructure of the Choroid Plexus in Vitamin A Deficient Rabbits
… blood in the subarachnoid space stretching the ependymal cells.</p> <p>The choroidal ultrastructure, as revealed by electron microscope showed in addition to the following: 1) weakened areas between endothelial cells comprising the capillaries with platelet thrombi often associated, 2) "free" …
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Meningeal Fibrosis in the Axolotl Spinal Cord: Extracellular Matrix and Cellular Responses
… pia mater. The role of reactive meningeal and ependymal cells is also investigated in regard to the deposition and remodeling of the fibrotic ECM, which is found to be similar in composition to hydrogel scaffolds being studied in mammalian SCI. It is shown that meningeal fibroblasts are the …
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Investigation of Tanycytes and Orexin Neurons in the KCNA1-Null Mouse Model of Epilepsy
… ectopic neurogenesis. Tanycytes are specialized ependymal cells lining the third ventricle (3V) and projecting to hypothalamic nuclei. They play a key role in maintaining the brain’s homeostasis. It remains unclear whether tanycytes are affected by SRS or whether metabolic interventions such as …
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Characterizing Changes in the Brain During Hydrocephalic Development and Exploring Potential Treatment Strategies
… without brain surgery. Choroid plexus epithelial cells (CPEC) are responsible for production of cerebrospinal fluid (CSF). Ependymal cells line the ventricles and play roles in CSF maintenance and waste clearance. Astrocytes perform various functions, one being blood-brain barrier (BBB) …
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The role of hydrodynamic forces in synchronisation and alignment of mammalian motile cilia
… (PCD) or asthma. In the brain, the multiciliated ependymal cells cover all the ventricles. Their cilia beat in a coordinated fashion to ensure the cerebrospinal fluid circulation necessary for brain homoeostasis, toxin washout and orientation of the migration of newborn neurons. Despite the …
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The role of retinoic acid in glioma growth control
… arising from the astrocytes, oligodendrocytes, ependymal cells or from glial progenitor cells. Although a relatively rare diagnosis, there is disproportionate morbidity associated with a glioma diagnosis, owing to its diffuse and infiltrative nature and partly, in the restricted accessibility of …
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Uncovering the role of notch signaling in development of hypothalamic nuclei in vivo and using in vitro microenvironments
… cellular subtypes of the brain such as glia, ependymal cells, and hypothalamic tanycytes. It is hypothesized that each of these cell types arise from a common progenitor early in development. Disruption during the developmental window of any of these cellular types can result in persistent …