Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"enzyme discovery"”.
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Developing Computational Methods in Proximity Pharmacology for Enzyme Discovery, PROTAC Screening, and Conformational Space Exploration
Traditional drug discovery focuses on small molecules that target single proteins. Molecular glues, discovered in the 1990s while studying natural products like cyclosporin, induce de novo protein-protein interaction between proteins. Later, heterobifunctional compounds consisting of two ligands …
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Transcriptomics-Guided Biodiscovery of Peroxidases from Macroalgae
Peroxidases are versatile enzymes with applications in laboratory analytics and industrial processes. Despite their relevance, many applications rely on a few well-characterized terrestrial enzymes, particularly horseradish peroxidase (HRP), whose complex post-translational modifications hinder …
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Functional metagenomic discovery and characterisation of CAZymes by microfluidic methods
Enzymes are the engines of life and the ideal reagents for efficient, sustainable biocatalytic processes. However, the compendium of currently known enzymes does not cater for all desirable activities or exhibit the required properties. Therefore, the discovery and thorough characterisation of new …