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Showing 1 to 2 of 2 for “"enzyme architecture"”.

  1. Enzyme Architecture and Flexibility Affect DNA Topoisomerase I Function

    van der Merwe, Mariè2016

    … topoisomerase I (Top1) is a highly conserved enzyme composed of four domains: a positively charged N-terminus; a DNA binding/core domain that circumscribes duplex DNA; a non-conserved linker domain; and a C-terminal/catalytic domain. Top1 catalyzes changes in DNA topology by transient cleavage …

    tenn-hsc Repository record

  2. Enzyme Architecture: The Role of a Flexible Loop in Activation of Glycerol-3-phosphate Dehydrogenase-Catalyzed Hydride Transfer

    He, RuiState University of New York at Buffalo2019

    M.S.

    buffalo Repository record