Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"environmental toxins"”.
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Environmental Toxins and Essential Trace Elements at Delivery and ADHD
Perfluorinated compounds (PFCs), phthalates, manganese and selenium are ubiquitous in the environment and humans and influence fetal growth and development. Register and biobank based case-control studies were conducted to investigate the relationship between prenatal exposure to these chemicals …
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Fluorescent probes and nanostructured materials for the detection of environmental toxins and catalysts development
La tesis trata sobre la síntesis y utilización de materiales modificados, para el reconocimiento de distintas sustancias por fluorescencia o para el desarrollo de catalizadores de reacciones orgánicas de interés. En la primera parte de la tesis se desarrollaron sensores de sustancias tóxicas como …
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Prenatal Environmental Stressors Impair Postnatal Microglia Function and Adult Behavior in Males
… dysfunction. However, it is unclear whether environmentally relevant immune activation, such as maternal immune activation during pregnancy produces a similar phenotype. Here I used a mouse model where pregnant females are exposed to a combination of two environmental toxins to investigate …
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The Intersection of Neurodegeneration and Mitochondrial Stress in Caenorhabditis Elegans Models of Parkinson's Disease
… attributed to a specific genetic mutation, thus environmental toxins must be investigated. When individuals with a genetic predisposition to PD are also exposed to environmental toxins, their risk is increased. We found that common soil bacteria, Streptomyces venezuelae (S. ven) produce …
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The Role of the Aryl Hydrocarbon Receptor in Tumor Growth and Chemoresistance
… and other cancers. The AHR is activated by environmental toxins, including polycyclic aromatic hydrocarbons, which are commonly found in cigarette smoke. It is hypothesized that activation of the AHR by these environmental toxins can contribute to the growth and chemoresistance of OSCCs. …
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The Association between Mercury Emissions and Individuals with Autism Aged from 3-21 in the State of California from 2001 to 2007
… the importance of examining the effect of environmental toxins and their impact on human health.</p>
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Perpetual Mobilization and Environmental Injustice: Race and the Contested Development of Industrial Agriculture in the Yazoo-Mississippi Delta.
… that agro-industry in the Delta is productive of environmental and social injustice, and that this injustice is confronted by black agricultural practice. A careful historical exploration of agro-industrial development avoids historical disjuncture by emphasizing the continuity between injustice …
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Effects of arsenic and UVB radiation on induction of cyclin D1 in human keratinocytes.
Arsenic and Ultraviolet radiation B (UVB) are environmental toxins that have been linked to various epithelial cancers. Arsenic metabolism in humans leads to its collection in the skin, where it encounters and can act with known carcinogen UVB. Epidemiological evidence of the two toxins …
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Systems approaches to identify molecular signatures from high-throughput expression data: towards next generation patient diagnostics
… by DNA mutations, pathogenic microorganisms, or environmental toxins. These perturbations lead to alterations in the abundance of intra/extracellular biomolecules, which offer diagnostic clues to the presence, as well as progression of disease. In this dissertation, I describe my investigations …
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Consequences and Limits of Cell-Cell Communication in Airway Immune Responses
… from viruses, bacteria, fungal spores, and environmental toxins. Conversely, when the immune system fails to respond or responds inappropriately in the airways, it can lead to diseases from deadly pneumonia to chronic allergies. Cell-cell communication is an important aspect of how airway …
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Transformational Educational Leader as Organizer and Administrator of a Movement Disorders Program
… and gene mutations, aging, trauma, viruses, environmental toxins, agricultural pesticides and herbicides, exposure to home pesticides and industrial chemicals and oxidative stress that contributes to nerve cell death. Ninety-seven people replied to the developed questionnaire that compared …
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IMPLEMENTATION OF 3D CELLULAR MODELS FOR DRUG AND TOXIN TESTING IN HEALTHY AND CANCEROUS TISSUE
… multiple materials for toxic effect, including environmental toxins, FDA recalled drugs , and chemotherapeutics. and charted the response of the organoids to these compounds. With liver and card iac organoids, t ests were performed that measured ATP activity, LIVE/DEAD viability and cytotoxicity …
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Molar pregnancy: A fifteen - year experience of a single tertiary institution
… maternal genetic translocations and environmental toxins. The only clear data relate to the impact of maternal age and the previous occurrence of a prior molar pregnancy (3,5,6). With minimal data from African countries about GTD, there remains a greater need for early recognition, …
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Changes in the Murine Nigrostriatal Pathway Following Pyrethroid and Organophosphate Insecticide Exposure: An Immunohistochemical Study
… nigrostriatal pathway and in the route by which environmental toxins may enter dopaminergic neurons.
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Novel Diagnostic Approaches for Genetic and Environmental Sources of Mitochondrial Dysfunction
… conditions, lifestyle choices and exposure to toxins also significantly contribute to their development. Unfortunately, early-stage diagnosis can be difficult due to overlapping symptoms with other diseases. Developing innovative therapies that can prevent or reverse the deterioration of …
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Differential Effects of Parkinsonian Toxins and L-DOPA on Locus Coeruleus and Substantia Nigra Neurons: Implications for Parkinson’s Disease
… inhibition and oxidative stress. Exposure to environmental toxins (such as the pesticide, rotenone) has been associated with the development of PD, and rare cases have shown a causal link (MPTP/MPP+) to the disease. There is also evidence that endogenous toxins (DA-derived 6-OHDA) may be …