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Showing 1 to 1 of 1 for “"entropic expansion"”.
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Small Molecule Binding to Disordered Proteins
… Chapter 2. I observed this interaction to be of entropic nature, and characterise the binding at the atomic level using simulations restrained with NMR data. The binding is extremely dynamic, such that both the small molecule and disordered protein explore many conformations in the bound state. …