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Showing 1 to 2 of 2 for “"enhancer biology"”.

  1. Investigating the function of DNA G-quadruplex structures in human enhancers

    … in diverse genomes, including promoters and enhancers. Enhancers interact with target promoters through 3D folding of interphase chromosomes to regulate gene transcription. However, the functional relevance of G4 structures at non- coding enhancer elements remains poorly understood. In this …

    cambridge Repository record for Investigating the function of DNA G-quadruplex structures in human enhancers (opens in a new tab)

  2. An Investigation of Epigenetic Mechanisms Driving The Biology of Head and Neck Squamous Cell Carcinoma

    … mutations in epigenetic regulators, the role of enhancer landscapes and overall chromatin dynamics have recently been recognized as important regulators of cancer cell activity and tumor microenvironment (TME) interactions. In the case of HNSCC, these facets of epigenetic regulation are …

    uthsc Repository record for An Investigation of Epigenetic Mechanisms Driving The Biology of Head and Neck Squamous Cell Carcinoma (opens in a new tab)