Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 48 for “"enhanced fluorescence"”.
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Photonic Crystal Enhanced-Fluorescence and Label -Free Bioimaging
In further work, a theory is outlined for predicting photonic crystal label-free imaging resolution based on resonance spectral characteristics. Devices are characterized by patterning a resolution standard onto the sensor using photolithography, and excellent design control over label-free imaging …
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Highly sensitive biosensors using photonic crystal enhanced fluorescence
Due to the importance of fluorescence assays in clinics, life science and genomic research, many nanostructures have been proposed to enhance the weak fluorescence signals from low abundance analytes. Among these structures, photonic crystal (PC) has attracted particular attentions because of its …
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Improved microarray sensitivity using photonic crystal enhanced fluorescence
… the proliferation of research on modifying fluorescence with optical resonances, there have been few evaluations of the practical impact of enhanced fluorescence on high-throughput biological assays such as microrarrays. This work details the application of photonic crystal (PC) surfaces as …
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Evanescent field enhanced fluorescence on a photonic crystal surface
… of angles for more efficient collection by a fluorescence detection system. The multiplicative effects of enhanced excitation and enhanced photon extraction combine to provide improved signal-to-noise ratios for detection of fluorescent emitters, which in turn can be used to reduce the limits …
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Photonic-plasmonic coupling enhanced fluorescence for digital-resolution protein detection
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01
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Cavity coupled photonic crystal enhanced fluorescence for high sensitivity biomarker detection
With the rise in fluorescence-based testing of biomarkers in samples, the use of dielectric optical resonators has increased dramatically. These photonic crystals make fluorophores emit more light through a process called enhanced fluorescence which in turn allows for more signal to be collected …
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Optimization of photonic crystal enhanced fluorescence by excitation laser angle scanning
Photonic crystal enhanced fluorescence (PCEF) has been demonstrated as an effective means for amplifying the excitation provided to surface-bound fluorescent molecules while simultaneously enhancing fluorescence emission collection efficiency. Optimal coupling of a fluorophore-exciting light source …
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Photonic crystal enhanced fluorescence for single-molecule biosensing and early disease detection
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-08-01
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Surface plasmon enhanced fluorescence for biological imaging : from visible to short-wave infrared
Fluorescence imaging offers high spatio-temporal resolution, low radiation dosage exposure, and low cost among all the available imaging modalities, for example, magnetic resonance imaging, computerized tomography and positron emission tomography. Imaging probes of high emissivity and …
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Designing, construction and analysis of line-scanning detection instrument for photonic crystal enhanced fluorescence
… detection instrument for photonic crystal enhanced fluorescence. In order to increase the fluorescence signal for low-concentration detection, we introduced the photonic crystal enhanced fluorescence detection modality and demonstrated that it is a very effective approach to improve the …
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Sensitive microarray-based biomarker detection using photonic crystal enhanced fluorescence and label-free imaging
Fluorescence-based biomarker detection in serum, saliva, urine, or breath condensate samples holds great promise for disease diagnostics and therapy monitoring because of its non-invasive nature. The microarray format, for its high-throughput and low analyte consumption characteristics, is …
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Development of selective peptide- and protein-based reporters of kinase activity utilizing chelation-enhanced fluorescence
… chromophore binds Mg + and undergoes chelation-enhanced fluorescence (CHEF). However, due to the BTF design limitation, only residues C- or N-terminal to the phosphorylated residue were used to specify the target kinase. To address this drawback, the recognition-domain focused (RDF) strategy, …
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Exploration of grating-based surface plasmon resonance systems for wave vector matching to enhance plasmon modes and preliminary surface plasmon-enhanced fluorescence interrogation
… techniques like infrared absorption, fluorescence, Raman spectroscopy, and surface chemistry reactions. This chapter will close by looking into the specific information on studies that will be found in subsequent chapters.</p> <p>Chapter 2 reveals information behind a study conducted …
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Optoperforation of Intact Plant Cells, Spectral Characterization of Alloy Disorder in InAsP Alloy Disorder in InAsP Alloys, and Bimetallic Concentric Surfaces for Metal-Enhanced Fluorescence in Upconverting Nanocrystals
… characterization of alloy disorder, and metal-enhanced fluorescence were applied to previously unconsidered or disregarded systems in order to demonstrate that such applications are both feasible and consequential. These applications were the subject of three disparate works and, as such, are …
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Advanced photonic crystal enhanced microscopy
… seeks to expand the field of photonic crystal enhanced microscopy by extending simple proof-of-concept experiments to advanced biological applications. There are four distinct projects that are related to a central theme: sophisticated microscope instrumentation for photonic crystal biosensing. …
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Harnessing Solid-State Ionic Transport for Nanomanufacturing and Nanodevices
… fabricated to study their effect on the Surface Enhanced Raman Scattering as well as Metal Enhanced Fluorescence of an adsorbate. New insight into whether farfield scattering of such structures or the nearfield EM-field is more important to the enhancement to Raman scattering was gained from …
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Aspects of charge recombination and charge transport in organic solar cells and light-emitting devices
… is used to guide the development of an OLED with enhanced fluorescence. The effects of nuclear disorder on optical and transport properties in organic semiconductors are examined and a general computational method for carrying out this analysis is described. The function of organic semiconductors …
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Next generation instrumentation for photonic crystal biosensors: a passage to early detection of cancer
… detection approach done using photonic crystal enhanced fluorescence (PCEF) instrumentation as the best way to achieve this goal. We introduce a model for predicting enhanced fluorescence (EF) performance of a photonic crystal (PC) in the context of a given set of instrument parameters as well …
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Studies of Titanium Dioxide Nanoparticles and Surfactants Effects, Singly and in Combinations, on Luminescence Intensity of Some Aromatic Compounds.
… The most dramatic effect was observed on the fluorescence intensity of pyrene. Pyrene showed enhanced fluorescence after degassing the solution alone or with the addition of the surfactants alone or in combination with TiO<sub>2</sub> after degassing. These results showed that surfactants and …
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Influence of metal nanoparticles on fluorescence properties
… and gold nanoparticles of various sizes on the fluorescence properties of tris (2, 2-bipyridyl) dichloro ruthenium (II) hexahydrate (Ru (bpy)3 2+), tryptophan and phenylalanine. For (Ru (bpy)3 2+) absorbed on silver and gold nanoparticles, the fluorescence intensity was quenched and showed a …
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