Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"endotoxin tolerance"”.
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Endotoxin Tolerance. Explorative studies in humans.
Contains fulltext : 74871.pdf (Publisher’s version ) (Open Access)
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Induction and characterization of endotoxin tolerance in equine peripheral blood mononuclear cells in vitro
… Individuals can become unresponsive to the endotoxin molecule after an initial exposure; this phenomenon has been called developing a state of "endotoxin tolerance" (ET). ET has been induced in horses in vivo; however, cytokine expression associated with ET has not been investigated. The …
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Modulation of macrophage and epithelial cell immune defences by probiotic bacteria: immune stimulation versus suppression
… muco-sal immune responses. These include, tolerance, associated with an M2-, regulatory macrophage phenotype and inflammatory activation with an M1-like phenotype. The cross-link between mucosal tolerance and inflammatory cytokine suppression, and augmentation of IL-10 production in the gut …
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Cellular Reprogramming in Skeletal Muscle after Repeated Exposures to Endotoxin
… disease. Heightened levels of circulating endotoxin is termed metabolic endotoxemia and has been linked to systemic inflammation which is associated with obesity, type 2 diabetes mellitus (T2DM), and cardiovascular disease (CVD). Immune cells exhibit a protective ability to develop …
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Quantitative analysis of TLR-4-mediated cell responses in murine macrophages
… pathways to regulate cytokine/chemokine release, endotoxin tolerance and apoptosis, which have been suggested to directly or indirectly participate in the regulation of innate and adaptive immune responses. However, little is known about their detailed signal-response relationships. In this …
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LPS from subgingival plaque and the periodontal pathogen Porphyromonas gingivalis, its effect on M1 and M2 macrophage responses and potential as a biomarker
… to induce a quiescent state known as endotoxin tolerance, thought to be a protective mechanism but which may also confer protective benefits to potential pathogens. Several bacteria, including keystone periopathogen Porphyromonas gingivalis (PG) is able to modify the bio-reactive …
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Intestinal macrophages in health and inflammation
… or TLR4, suggesting it was not simply a form of endotoxin “tolerance”. However, the mechanism seemed to involve IL-10, as colonic mφ from IL-10-deficient animals displayed a heightened level of TLR expression and responsiveness, even prior to the onset of intestinal inflammation. In Chapter 5, I …
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Expression von pro- und antiinflammatorischen Zytokinen in Kupfferzellen der Rattenleber unter Normal- und Entzündungsbedingungen
… als in der Kontrollratte exprimiert.Eine Endotoxintoleranz von Makrophagen und Monozyten nach repetitiven LPS-Reizen wurde beschrieben. Während ein kurzfristiger in-vitro-LPS-Reiz in einer pathophysiologisch relevanten Konzentration von 1 ng/ml die proinflammatorischen Zytokine TNFα und …