Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"endothelium-dependent relaxation"”.
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Effects of an Endothelial Cell-specific PAR2 Knockout on Endothelium-dependent and -independent Relaxation of Mouse Arteries
… PAR2 deficient mice (EC PAR2-/-) to investigate endothelium-dependent and -independent mechanisms of vascular smooth muscle relaxation. The findings indicate EC PAR2-/- mice exhibit reduced capacity for endothelium-dependent relaxation (EDR) of vascular smooth muscle in resistance-type arteries. …
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Role of SFLT-1 in vascular regulation in pregnancy and its effect on fetal vascular programming
… arteries and uterine arteries, and impaired endothelium-dependent relaxation in uterine arteries of sFlt-1-treated group toward the end of gestation. In addition, pregnant mice over-expressing sFlt-1 displayed a progression toward increased expression of HIF-1á and TGF â3 and decreased …
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Role of kinins in mediating vascular function in healthy pregnancy and pre-eclampsia
… Kinins are endogenous peptides released by the endothelium that contribute to the regulation of cardiovascular homeostasis by inducing vasodilation, fibrinolysis and angiogenesis. Given that pre-eclampsia is associated with reduced endotheliumdependent relaxation, coagulation abnormalities and …
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Oxidative stress in endothelial cells of patients with coronary artery disease
… significantly elevated O2- levels and impaired endothelium-dependent relaxation in portions of saphenous vein from patients with CAD related to those from healthy control subjects. In addition, results demonstrated more severe endothelial dysfunction in vessels from CAD patients with T2D …
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MAPK and pro-inflammatory mediators in the walls of brain blood vessels following cerebral ischemia
… of spasmogenic substances, and inhibition of endothelium dependent relaxation [60, 61]. It is suggested that the extravasated blood could induce generation of free radicals that subsequently may exert a direct local toxic effect on the cerebral arteries [62, 63]. G-protein coupled receptors …