Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"endothelial-to-haematopoietic transition"”.
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Role of the cell cycle during human endothelial-to-haematopoietic transition
Haematopoietic stem cells (HSC) are responsible for the maintenance of blood homeostasis and are of fundamental importance for the treatment of a variety of life-threatening diseases. However, their scarce availability constitutes a major obstacle. Thus, understanding their embryonic specification …
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Using single cell transcriptomics to characterise endothelial populations in embryonic haematopoiesis
Haematopoietic stem cells (HSCs) possess the unique ability to reconstitute an animal’s entire haematopoietic system. As such, it is inherently interesting to the fields of regenerative medicine and developmental biology to understand how these cells first form in the embryo. Haematopoietic stem …
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The Role of Gata3 in Blood Stem Cell Emergence
The first definitive haematopoietic stem cells (HSCs) produced during embryonic development are generated from a specialised subset of endothelial cells known as haemogenic endothelium. Recently, it was reported that Gata3 plays a dual role in the development of sympathetic nervous system and …