Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 117 for “"endothelial function"”.
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Associations between affective traits and endothelial function in depressed adults
… or low positive affect) are associated with endothelial function, a marker of cumulative CVD risk. In addition, because the other affective traits overlap with depressive symptom severity, this study’s second aim was to investigate which components of pairs of affective traits (shared versus …
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Investigating the impact of flavonoid metabolites on endothelial function and vascular inflammation
… on vascular and inflammatory biomarkers of endothelial dysfunction. 20 flavonoids and metabolites were screened for their effects on endothelial nitric oxide synthase (eNOS), haem oxygenase-1 (HO-1/Hmox-1), and vascular cell adhesion molecule-1 (sVCAM-1) in endothelial and smooth muscle …
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Characterisation of the expression profile and endothelial function of Rho GTPase RhoJ
… identified RhoJ as being highly expressed in endothelial cells. The aim of this project was to investigate the expression pattern and endothelial function of RhoJ, particularly in the processes necessary for angiogenesis. Silencing RhoJ with siRNA impaired tube formation and migration. On the …
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The effects of cocoa flavanol supplementation on endothelial function and exercise performance.
… have gained attention from beneficial effects on endothelial function and exercise performance, especially in clinical populations. Few studies have utilized healthy college-aged adults. Twenty college-aged males and females completed this randomized, double-blind study. Participants completed 14 …
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Examining endothelial function in humans in vivo: improving guidelines and exploring novel measures
… 1 introduced the old and new measurement of endothelial function, and vascular health. The first part of this thesis focussed on the “old” flow-mediated dilation measurement, introduced in 1992, which relies on brachial artery vasodilation after a hyperaemic stimulus (e.g. after occlusion of …
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The impact of obesity and fitness on endothelial function in polycystic ovarian syndrome
… cardiovascular disease (CVD) risk profile. Endothelial dysfunction, an early barometer of CVD, has been exhibited by women with PCOS; however, it remains unclear whether endothelial dysfunction is independent of CVD risk factors in this population. Exercise training has been found to enhance …
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The Impact of Mental Challenge on Indicators of Endothelial Function in Obese Individuals
… have examined psychological stress-induced endothelial dysfunction, however, the underlying mechanisms for these responses have not been clearly elucidated. The purpose of this study was to compare the effects of mental challenge on forearm blood flow, total antioxidant capacity (a measure …
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Assessment of the Impact of Loading Pressure on Endothelial Function in Diabetic Foot
… complication of diabetes. High pressure and endothelial dysfunction are two major contributing elements in the development of diabetic foot ulceration. <b><br/></b><b><br/></b><b>Aim of the study</b>: To investigate foot pressures experienced on both dorsal and plantar surfaces of the foot, …
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Identifying Depression Utilizing Tumor Necrosis Factor–[alpha] and Endothelial Function in Spinal Cord Injury
… of tumor necrosis factor-alpha (TNF-α), and endothelial function in people with SCI. SCI participants showed higher levels of depression, TNF-α and shorter time to reach maximum level of nitric oxide (NO)-dependent vasodilation. Although these alterations co-exist, no direct linkage among …
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Microfluidic-based 3D cell culture for studies of biophysical and biochemical regulation of endothelial function
… biochemical induced sprouting was demonstrated. Endothelial cells sprout from an intact monolayer to form multicellular capillary-like structures. Furthermore, using time-lapse microscopy the cellular dynamics during sprouting angiogenesis were observed with great detail, showing tip cell …
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Developing a Technique to Create a Uniform, Targeted, Transient Shear Stress Stimulus to Assess Endothelial Function
… dilation, FMD). FMD as an index of endothelial function is stimulated by an uncontrolled increase in shear stress created with limb occlusion release [reactive hyperemia (RH)-FMD]. RH-FMD interpretation is complicated because differences in RH-FMD between groups/conditions may …
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Can exercise mediate similar beneficial effects on endothelial function and endothelial reperfusion injury as ischemic preconditioning?
… exercise is able to provide protection against endothelial ischemia reperfusion (IR)-injury (Seeger et al., 2015). However, more research is warranted to further explore the potential of (single bouts of) exercise as a form of preconditioning and to determine the most effective way to employ it. …
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Acute exercise and postprandial triglyceride metabolism: mechanisms for the exercise effect and implications for endothelial function
… 2. determine the influence of acute exercise on endothelial micropartlcles and soluble adhesion molecules, plasma biomarkers of endothellal dysfunction, in the fasted and postprandial states 3. investigate the mechanisms mediating the exercise attenuation of postprandial lipemia, and in …
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Sex differences in aortic endothelial function of diabetic rats: Possible involvement of superoxide and nitric oxide production
… whether there were sex differences in rat aortic endothelial function in diabetes, and to examine the potential roles of superoxide and nitric oxide (NO) in this sex-specific effect. Two diabetic animal models were used: streptozotocin (STZ)-induced type 1 diabetic rats (at early and intermediate …
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The effect of freeze dried whole watermelon powder on endothelial function and vascular health in older adults
… powder on cardiovascular biomarkers and endothelial health. In a 16-week double-blinded, randomized placebo-controlled study design, 38 men and women between the ages of 45 to 79 years old consumed whole freeze dried watermelon powder or placebo powder (control). An EndoPATⓇ was used to …
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Sex differences in mesenteric endothelial function of streptozotocin-induced diabetic rats: The role of endothelium-derived relaxing factors
… the mesenteric expression of the mRNAs for endothelial nitric oxide synthase (eNOS) and NADPH oxidase (Nox) in STZ-induced diabetes in both sexes. Vascular responses to acetylcholine (ACh) in mesenteric arterial rings pre-contracted with phenylephrine were measured before and after …
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