Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"endothelial colony forming cells"”.
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Multi-Scale Osteointegration and Neovascularization of Biphasic Calcium Phosphate Bone Scaffolds
… and (2) human umbilical cord blood-derived endothelial colony forming cells have potential for promoting neovascularization in a bone defect when combined with rhBMP-2.
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Vasogenic bloodborne progenitors and diabetes
… attributed to a dysfunction of reparative cells called Endothelial Progenitor Cells (EPCs). EPC is an umbrella term applied to three distinct populations of vasoactive progenitors which contribute to adult (postnatal) angiogenesis in different ways. The circulating EPC can be identified via …
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Rapid formation of cell-mediated microvascular networks in collagen, fibrin, and puramatrix provisional matrices
… in the possibility of delivering vascular cells for therapy of ischemic diseases. To address these challenges, we developed a vascularization model in which human endothelial colony-forming cells (ECFCs) and mesenchymal progenitor cells (MPCs), coinjected with a solubilized extracellular …
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Potential of endothelial progenitors to reverse choroidal atrophy during age related macular degeneration
… detrimental to cell survival. To introduce cells into an area suffering from severe oxidative stress may risk exacerbating matters, if the cells are likely to become apoptotic or necrotic and adding to the noxious conditions of the environment. If a cell therapy is to be considered, steps …
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Pathogenicity assessment of genetic variants in von Willebrand disease using quantitative, qualitative, and functional approaches
… circulating VWF is synthesised and released by endothelial cells (ECs). VWD is caused by rare DNA sequence variants in the VWF gene. However, coupling genotype with phenotype is complicated by factors including incomplete penetrance and the trans-acting effect of the ABO histo-group. High …
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¿ROLE OF ENDOTHELIAL DYSFUNCTION IN THE PATHOGENESIS OF UNPROVOKED VENOUS THROMBOEMBOLISM¿
… the development of novel therapeutic strategies. Endothelial dysfunction (ED) plays a crucial role in promoting thrombus formation, yet its presence in uVTE patients has been poorly investigated, so far. Therefore, in this study we investigated ED in uVTE, using patient-derived endothelial …
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Characterisation of endothelial cell metabolic plasticity and vascular remodelling in the retina
… of flux through this pathway in some non-retinal endothelial cell types has been shown to vary in disease conditions. This PhD project has assessed the nature of glycolysis and related plasticity in human retinal microvascular endothelial cells (HRMECs) exposed to in vitro conditions relevant to …