Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"endoreduplication"”.
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Endoreduplication in green algae: Its mechanistic basis and potential for increased biofuel production
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-12-01
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Adaptation of an invasive grass to agriculture: ecological and genomic evidence
… between phenotypic variation and genomic endoreduplication responses to the common stresses herbicides, competition, and clipping. Endoreduplication occurs when plants increase their genome size by increasing their nuclear chromosome number, with some evidence showing correlations with …
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Potato genomics three ways: quantification of endoreduplication in tubers, a romp through the transposon terrain, and elucidation of flower color regulation
… and evaluation of a protocol to characterize endoreduplication within potato tubers, demonstrating substantial variation between tissue types and among wild species which may facilitate research into the genesis and growth of these starchy underground stems. Next, we transitioned to explore …
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Constraints on plant resistance and tolerance trade-offs
… in the lab have shown that the process of endoreduplication is the primary mechanism by which plants compensate for lost tissue following mammalian herbivory (Scholes et al. 2011). Moreover, the gene G6PD1 was also found to play a significant role in the compensatory process, which is the …
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The adaptive potential of plant endopolyploidy in response to herbivory
… cell cycle under genetic regulation, termed endoreduplication (Brodsky and Uryvaeva 1977, Nagl 1976). Removal of apical dominance by herbivory reduces the level of auxin in the remaining above-ground tissues and leads to axillary bud break and stem regeneration—high levels of auxin are also …
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Telomere-Driven Tetraploidy and its Relevance to Cancer
… into S phase, and whole genome reduplication. Endoreduplication requires an ATM and/or ATR-dependent DNA damage signal, blocking the activation of Cdk1/CyclinB and mitosis. Furthermore, we demonstrate tetraploidization through endoreduplication or mitotic failure in human broblasts and mammary …
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Re-replication in the Absence of Replication Licensing Mechanisms in Drosophila Melanogaster
… in G2 arrested cells result in a complete endoreduplication. In contrast to the ordered replication of euchromatin and heterochromatin during early and late S-phase respectively, endoreduplication induced by Dup over-expression does not exhibit any temporal order of replication initiation …
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Genetic improvement of selected indigenous Cucurbitaceae species important for food and medicinal purposes in KwaZulu-Natal, South Africa
… However, in higher plants nuclear DNA endoreduplication often occurs during their growth and differentiation which causes polysomaty in their tissues. For both C. palmata and L sphaerica, the optimum germination conditions were 25°C under light. Growth was either in the nursery (in …
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The Role of Pot1 in Telomere Protection and Maintenance
… novel telomere dysfunction phenotype, extensive endoreduplication. However, POT1a/b were largely dispensable for repression of telomere fusions, which is a prominent outcome of inhibition of another telomere binding protein, TRF2. Previous structural analysis of POT1 and its binding partner TPP1 …
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Gene expression profiling in different stages of development of Arabidopsis thaliana leaftrichomes at the single cell level
… this cell changes its cell cycle: it starts endoreduplication (a modified cell cycle in which DNA replication continues in the absence of mitosis and cytokinesis). This makes trichomes a suitable model for studying cell cycle regulation, regulation of cell development and differentiation. …
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Global analysis of the transcriptional regulation of Sinorhizobium meliloti cell cycle progression and study of cell cycle regulation during symbiosis with Medicago sativa
… permeability, cell elongation and branching, endoreduplication of the genome and loss of reproductive capacity and therefore a significant deviation from the free-living cell cycle program. Endoreduplication of the genome requires a decoupling of DNA replication and cell division, which could …
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The structure and evolution of breast cancer genomes
… landmark event in the evolution of the genome - endoreduplication (duplication of its entire genome). Genome rearrangements and sequence-level mutations were fairly evenly divided between earlier and later, implying that genetic instability was relatively constant throughout the evolution of the …
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Trophoblast specification and differentiation potential in early human and non-human primate embryogenesis
… Marmoset TSCs form syncytiotrophoblast by endoreduplication as determined by live imaging. Removal of EGF promotes a peri-implantation like phenotype that can form correctly polarized trophoblast spheroids. Moreover, implantation of marmoset TSC spheroids into extracellular matrix marmoset …
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Mechanisms of bullseye boundary formation in Hibiscus trionum petal patterning
… protocol. As an increase in cell ploidy due to endoreduplication often accompanies cell differentiation, this will allow me to test for a correlation between cell size and nuclei size across the petal epidermis. Besides using cell geometry to track boundary establishment, I also identified …
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Isolation and characterization of the SIAMESE family: a novel class of cell cycle regulators in plants
Recessive mutations in the SIAMESE (SIM) gene of Arabidopsis result in multicellular trichomes harboring individual nuclei with a low ploidy level, a phenotype strikingly different from that of wild-type trichomes, which are single cells with a nuclear DNA content of approximately 16-32C. These …
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Functional genomics of plant compensatory responses
… and c) through an increase in DNA content (via endoreduplication) that feed metabolites to pathways involved in defense through transcriptional programming (Scholes and Paige, 2011). Collectively, these results, indicate the direct or indirect importance of G6PDH1and invertase isoenzymes in …