Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"endometrial stromal cell"”.
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Identification of molecular signaling pathways underlying human endometrial stromal cell differentiation
Decidualization, the differentiation of endometrial stromal cells, is essential for a successful pregnancy. Although the steroid hormones estrogen (E) and progesterone (P) are known to control decidualization, the precise mechanisms via which these hormones act to control this differentiation …
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Role of Extracellular Signal-Regulated Kinase and Peroxisome Proliferator-Activated Receptor gamma on Transforming Growth Factor-β1-Induced Human Endometrial Stromal Cell Decidualization
… of ERK and PPAR gamma on TGF-β1-induced human endometrial stromal cell decidualization in vitro. MATERIALS AND METHODS: Human endometrial tissues obtained by hysterectomy specimens from patients with conditions other than endometrial diseases such as leiomyoma. Endometrial stromal cells were …
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Endometrial Decidualization by TGF-β and PPAR-γ
OBJECTIVE: Endometrial decidualization is essential for implantation and pregnancy, so we investigated the interaction of TGF-β and PPAR-γ on decidualization using cultured human endometrial stromal cell. METHODS: Human endometrial tissues were examined immunohistochemically for the expression of …
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The Possible Role for Basigin Receptor Function in The Induction of Matrix Metalloproteinase Expression in Human Endometrial Stromal Cells
… shown to induce MMP expression in vitro in human endometrial stromal cell lines (HESC). Understanding how basigin induces matrix metalloproteinases within normal cellular conditions will help researchers understand how these signaling cascades flow in the framework of implantation. In order to do …
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Role of Chlamydia trachomatis infection in adverse pregnancy outcomes
… unknown. A successful pregnancy requires normal endometrial stromal cell (ESC) decidualisation and trophoblast invasion, processes that involve chemokine action and lead to successful implantation. My objectives were to determine whether Ct infection impacts upon ESC decidualisation and chemokine …
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Analysis of the Role of the Transcription Factor-C/ebpbeta in Implantation
… proliferation and differentiation of uterine stromal cells. The molecular pathways underlying this hormonally induced cellular transformation, an essential prerequisite for embryo implantation, are poorly understood. We previously identified the transcription factor C/EBPbeta as a target of …
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Analysis of the role of the transcription factor-C/EBPβ in implantation
… proliferation and differentiation of uterine stromal cells. The molecular pathways underlying this hormonally induced cellular transformation, an essential prerequisite for embryo implantation, are poorly understood. We previously identified the transcription factor C/EBPβ as a target of …
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Role of Msx homeobox genes in uterus during embryo implantation
… cytokines, transcription factors, and extracellular matrix proteins as potential regulators of this complex process. This dissertation work investigates the critical role of Msx homeobox genes in the uterus during embryo implantation. The mammalian Msx homeobox genes, Msx1 and Msx2, encode …
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Estrogen signaling during decidualization
… by the deciduous transformation of fibroblast endometrial stromal cells to morphologically and functionally unique decidual cells along with the formation of extensive neo-angiogenic networks that play pivotal role in nourishing the developing embryo. Steroid hormones estrogen (E) and …
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Loss of basigin expression in the uterus reduces fertility in female mice
… a transmembrane glycoprotein expressed in many cell types. It is involved in neurological processes, lymphocyte migration, angiogenesis, tissue remodeling and lactate transport. Our data show that Bsg is expressed in the reproductive tract and is important for fertility in both males and …