Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"endoglycosidase"”.
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Bacterial modulation of host glycosylation - in infection, biotechnology, and therapy
… and for therapeutic use. The role of IgG endoglycosidase EndoS in streptococcal virulence was evaluated in a murine model of invasive infection and we found significant contribution when heterologously expressed. We also discovered and characterized EndoS2, a novel enzyme specific and …
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N-linked glycosylation of ether á go-go potassium channels: effects on cell surface expression and functional properties
… der core-Oligosaccharide. Diese Stelle ist Endoglycosidase H-sensitiv und wird von Concanvalin A erkannt. Die Mutation dieser Stelle hatte keinen signifikanten Einfluß auf die intrazelluläre Lokalisierung und die funktionellen Eigenschaften von hEag1 Kanälen, wenngleich eine Auswirkung auf …
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Isolation and characterization of cathepsin Z, a lysosomal cysteine proteinase
… Cathepsin Z is susceptible to digestion by endoglycosidase H, and oligosaccharides comprise 3.1 kDa of the reduced molecular weight. The expression of cathepsin Z was not affected by differentiation of U-937 cells with phorbol ester, unlike the expression of cathepsins B and S. …
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On the immunopathogenesis of systemic lupus erythematosus - Immune complexes, type I interferon system, complement system and platelets
… the final paper we found that EndoS, a bacterial endoglycosidase, abolished all pro-inflammatory properties of ICs isolated from SLE patients (Paper V). Thus, we suggest that EndoS has the potential to be developed as a new therapy against SLE considering its potent IC-modulating effects. In …
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The Nuclear Pore Complex: Novel Glycoprotein Constituents
… and the M<sub>r</sub> of p62 is not affected by endoglycosidase H. Thus, the addition of GlcNAc appears to be carried out by a cytoplasmically disposed transferase and is clearly distinct from the N- and O-linked glycosylation pathways in the endoplasmic reticulum and Golgi complex. I have also …
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Molecular investigation if the rat jejunal active nucleoside transport protein rCNT1
… the present study has shown, from the effect of endoglycosidase F treatment of the protein expressed in xenopus oocytes, that the C-terminal hydrophilic domain of the protein is N-glycosylated and so must in fact be extracellular. Furthermore, mutagenesis of rCNT1 cDNA allowed for the production …
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Dietary carbohydrates influence the structure and function of the intestinal alpha-glucosidases
… HMW SI species in cells treated with maltose. Endoglycosidase treatment of immunoprecipitated SI showed that increased molecular weight is a consequence of additional N- and O-glycosylation of the enzyme. In comparison to the control, the HMW SI was found to be more associated with lipid rafts …
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Liver Cell Adhesion Molecules in Embryonic Development
… chains is susceptible to cleavage by endoglycosidase H, suggesting that it is of the high-mannose type; the other three are probably of the complex type. Antibodies to L-CAM inhibit calcium-dependent cell-cell adhesion between liver cells in a rotary suspension culture. The same …