Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"endoderm development"”.
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The role of pou2/spiel-ohne-grenzen (spg) in brain and endoderm development of the zebrafish, Danio rerio
The central theme of development, how cells are organized into functional structures and assembled into whole organisms, is addressed by developmental biology. One important feature of embryonic development is pattern formation, which is the generation of a particular arrangement of cells in …
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Endodermal Patterning in Xenopus laevis
The endoderm is the inner germ layer of the vertebrate embryo from which the respiratory and digestive systems are derived. These include organs such as the liver, pancreas, stomach, lungs and intestine. Recent research has helped our understanding of early vertebrate endoderm specification and …
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The Role of Sox17 in Normal and Pathological Beta Cell
… factor and a key regulator in various developmental and disease contexts. During endoderm development, Sox17 acts, in part, by transcriptionally regulating other important endodermal transcription factors including HNF1β and Foxa2, which are also known regulators of postnatal β cell …
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The role of transcription factor GATA6 in the development of the human pancreas
… been in mice. The paucity of research in the development of the human pancreas has led to diminished knowledge in the area, compared to other species. Recent discoveries provide growing evidence for discrepancies between mouse and human pancreatic development and diseases and highlight the …
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FGF signaling in specification of hESC-derived definitive endoderm
… assay for understanding human pancreas development. Pancreas originates from the definitive endoderm (DE), one of the three germ layers. The path from definitive endoderm to pancreatic progenitor cells and finally the insulin producing beta cells involves sequential cell-fate decisions …
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ENDOTHELIAL- EPITHELIAL INTERACTIONS Blood vessels friends or foes?
… to understand how these cells form during embryo development. By the use of mice we have been able to study how blood vessels regulate the growth of the precursors of β cells. We have also been able to show that the formation of a tubular system in the pancreas is important for the regulation of …