Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"endocytic recycling"”.
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A Molecular Mechanism for Endocytic Recycling of the M5 Muscarinic Acetylcholine Receptor
… AGAP1 and activity of AP-3 were required for the endocytic recycling of M5 in neurons, the lack of which resulted in downregulation of cell surface receptor density. M5 has been shown to be expressed in the dopaminergic neurons of the ventral midbrain and to function in the presynaptic modulation …
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Engineering Optogenetic Control of Endocytic Recycling: Controlling Rab11 Function in Drosophila melanogaster using Engineered Light-Responsive Nanobodies
… is Rab11. Rab11 is responsible for endosome recycling: returning membrane proteins and receptors from intracellular recycling endosomes to the cell membrane, where these membrane proteins and receptors may be reused. Although the exact mechanism of Rab11 trafficking is not known, Rab11 …
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The Functional Synergy Between Yeast Dynamin and Key Membrane Recycling Factors
Endocytic recycling is the process by which cells recycle endocytic materials from the trans-Golgi network or endosome back to the cell membrane, as opposed to being targeted to the vacuole for degradation. Ypt31p and Ypt32p GTPases are known to regulate the function of F-box protein Rcy1p, which …
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Molecular and Cellular Investigations of Prader-Willi Syndrome
… to PWS phenotypes such as hypogonadism and endocytic recycling, we found a delay in neurogenesis in the PWS neurons. In Chapter 5, we focused our attention on another obesity disorder for comparison. We used RNAseq to determine the transcriptional similarities and differences between PWS, …
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The Role of Membrane Domains In Protein and Lipid Sorting During Endocytic Traffic
… energetically costly, the cell depends on active recycling to return endocytosed membrane components back to the PM. For most proteins, the mechanisms and pathways of their PM retention remain unknown. The work presented here shows that association with ordered membrane microdomains is fully …