Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"endocrine disrupting chemical"”.
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Chronic effects of single intra-peritoneal injection of endosulfan on rainbow trout (Oncorhynchus mykiss) and field observations of caged rainbow in Oshawa Creek
… some evidence to support that it may act as an endocrine disrupting chemical. Juvenile rainbow trout (Oncorhynchus mykiss) were caged at 4 sites in Oshawa Creek during the fall and spring of 2008 and 2009 while another group was intra-peritoneal injected in the laboratory with varying …
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Circulating sex hormone levels in rats: a systematic analysis of the literature and perinatal BPA study
… we also examined the effect of the known endocrine disrupting chemical, bisphenol-A (BPA), at environmentally relevant ranges on the sex hormones, follicle-stimulating hormone (FSH), luteinizing hormone (LH), T, E2, and P4 in perinatally exposed, infantile rats. We found no effect of BPA …
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Prenatal exposure to di-(2-ethylhexyl) phthalate and high-fat diet synergistically disrupts mouse fetal oogenesis and affects folliculogenesis
Di-(2-ethylhexyl) phthalate (DEHP) is a chemical that is widely used as a plasticizer. Plasticizers are chemicals that are added to materials to increase flexibility, durability, and strength. DEHP is abundant in products such as food storage containers, containers of personal care products, …
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Effects of Short-Term Exposure to Octylphenol and Genistein on the Immune System of C57BL/6 and (NZBxNZW)F1 Mice
… and genistein are two of the growing list of endocrine disrupting chemicals found in the environment that mimic estrogen in reproductive tissue both in vitro and in vivo. It is well established that endogenous estrogens modulate not only the reproductive system, but also the immune system. …
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Mechanism of Bisphenol A toxicity in adult mouse ovarian antral follicles
Bisphenol A (BPA) is an endocrine disrupting chemical widely used in the manufacturing of commonly used consumer products containing polycarbonate plastics, epoxy resins, dental sealants, and receipt paper. During a process called leaching, the ester bonds maintaining BPA polymers can break, …
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Developing disease-state liver models to determine the effects on brain function in vitro
… for filtering and detoxifying harmful chemicals from the body. Because of its role as the barrier between the gut and the circulatory system, and due to the brain’s high perfusion rate, the liver’s function as a regulator for blood composition is highly important for the brain. Although …
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Individual and Combined Effects of Selected Emerging Safeners: Mefenpyr di-ethyl and Cyprosulfamide and their Co-Herbicides, Fenoxaprop-P-ethyl and Isoxaflutole on Daphnia magna and Danio rerio
… varied in the environment in relation to their chemical properties, such as octanol-water solubility partition coefficient. Herbicides and safeners have been found in the aquatic environment because they could dissipate from the point of application through leaching, surface runoff, and …
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An integrative analysis of the multi- and transgenerational effects of endocrine-disrupting chemicals on behavior and neurobiology
Endocrine-disrupting chemicals (EDCs) are ubiquitous environmental pollutants that are known to interfere with hormone action. Exposure to EDCs during hormone-sensitive periods of prenatal development can result in disease and dysfunction later in life. Furthermore, EDC effects have been reported …
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The immediate and long-term consequences of temporary exposure during adulthood to di(2-ethylhexyl) phthalate and diisononyl phthalate on female reproduction
… bone density, and neurological health. Thus, chemical exposures that target the ovary can lead to disruptions in reproductive and overall health. The phthalate chemical family has several prominent members with endocrine disrupting capabilities. One of the most common phthalates is …
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The transgenerational effects of Di(2-ethylhexyl) phthalate on female reproduction in mice
… numerous consumer products and is a ubiquitous chemical. Humans are exposed to DEHP daily due to its widespread use and ability to leach from out of products. DEHP and its bioactive metabolites are found in human tissues such as amniotic fluid, cord blood, breast milk, and human follicular …
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The effects of adult exposure to genistein on female reproductive outcomes
… biosynthesis pathway, and is categorized as an endocrine disrupting chemical. This is of concern to human health because genistein-induced effects on the steroidogenic pathway can result in adverse, long-term effects on female fertility, cardiovascular, bone, and overall health. The ovary is an …
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Investigating persistent organic pollutants as endocrine disruptors of androgen receptor signalling
Man-made chemicals are a part of everyday life and may mimic hormonal signalling in wildlife and humans. These exogenous mixtures or substances are called endocrine disrupting chemicals and may lead to adverse health effects in those exposed. Persistent organic pollutants (POPs) are a class of …