Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 53 for “"endocarditis"”.
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Rheumatic endocarditis in children
The term "Rheumatism" has probably been ascribed by the profession to diseases which are essentially different both pathologically and clinically. To term a condition "rheumatic" is too often to cloak one's ignorance of what the true diagnosis is. In spite of the careful and tedious researches of …
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The changing landscape of infective endocarditis in South Africa
… profile and outcomes of patients with infective endocarditis (IE) in South Africa. Methods. We conducted a retrospective review of the records of patients admitted to Groote Schuur Hospital between 2009 and 2016 fulfilling universal criteria for definite or possible IE, in search of demographic, …
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Profile, Presentation and Outcomes of Prosthetic Valve Endocarditis in a South African Tertiary Hospital: Insights From the Groote Schuur Hospital Infective Endocarditis Registry
Background Prosthetic valve infective endocarditis (PVE) is associated with high morbidity and mortality. The prevalence of PVE in local retrospective studies ranges between 13% and 16%. However, the clinical patient profile and outcomes remains unknown. Methods We performed a prospective …
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Measurement of the Association Between Mean Platelet Volume and Embolic Complications of Infectious Endocarditis
… platelet volume (MPV) and embolic disease of endocarditis. This work seeks to assess this association in the largest cohort to date and become the first to assess MPV in injection drug use associated endocarditis cases (IDU-IE). Methods: Patient charts from 1/1/2004 - 9/31/2015 were manually …
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Infant and Childhood Infective Endocarditis in the Western Cape, South Africa: A Retrospective Review
Introduction Infective endocarditis is a microbial infection of the endothelial surface of the heart, predominantly the heart valves, that is associated with high mortality and morbidity. Few contemporary data exist regarding affected children in our context. Aims and Objectives: We aimed to …
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Caracterización clínica, microbiológica y ecocardiográfica de pacientes con Endocarditis infecciosa en la Fundación Cardioinfantil 2002-2012
Introducción: La endocarditis infecciosa es una infección microbiana del endocardio poco estudiada en nuestro país, la cual se asocia con múltiples complicaciones clínicas, y que presenta una mortalidad importante, que no ha disminuido a lo largo del tiempo sin importar los cambios epidemiológicos, …
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Proyecto ENDOKINETIC-CEF: tratamiento de la endocarditis infecciosa por Enterococcus faecalis en programas de tratamiento antibiótico endovenoso domiciliario
Esta tesis doctoral explora el tratamiento de la endocarditis infecciosa por Enterococcus faecalis para su utilización en los programas de tratamiento antibiótico endovenoso domiciliario (TADE), prestando especial atención a la adaptación a estos programas del tratamiento con la combinación de …
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Endocarditis infecciosa en el Hospital Central de Asturias: alternativas diagnósticas y terapéuticas. Estudio de enterococcus spp. como agente etiológico emergente
La endocarditis infecciosa (EI) se define como una enfermedad multisistémica que resulta de la invasión, generalmente bacteriana pero también fúngica, de la superficie endocárdica valvular y/o mural del corazón o del material protésico intracardiaco. Se trata de una entidad clínica compleja debido …
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Long term outcome and the validity of EuroSCORE II in native-valve surgery for active endocarditis in a South African cohort
Infective endocarditis was initially described in the early 16th century and only methodically reviewed after the 19th century when Osler gave the drive to the Royal College of Physicians in 1885 through his contribution. The last 25 years has not shown much change in the mortality from infective …
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Doença de Whipple e endocardite tricúspide: um relato de caso
… evaluation showed associated tricuspid valve endocarditis. With treatment for WD the patient showed resolution of classic symptomatology as well as regression of the valvular vegetations. This study reports a case of WD with classic manifestation associated with isolated tricúspide valve …
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The clinical utility of tissue polymerase chain reaction, tissue culture, and tissue histology in blood-culture negative infective endocarditis - a South African single hospital experience
Background. Infective endocarditis (IE) poses significant diagnostic and therapeutic challenges, especially in blood culture-negative infective endocarditis (BCNIE) cases. Appropriate antimicrobial therapy is guided by knowledge of the causative organisms and their characteristics. Amongst patients …
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Technical evaluation of a Real-time polymerase chain reaction (PCR) assay for the detection of Bartonella spp for diagnostic purposes
Infective endocarditis (IE) is a rare disease affecting heart tissues. The laboratory diagnosis of culture-negative endocarditis is complicated, and largely based on the combination of nucleic acid detection methods and serological investigation. There is a paucity of published data on microbes …
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The Role of Streptococcus Gallolyticus Subspecies Gallolyticus In Colon Cancer Development
… patients with either <em>Sg </em>bacteremia or endocarditis it was found that 25-80% of patients with <em>Sg </em>bacteremia had tumors and 18-62% of patients with <em>Sg </em>endocarditis had colonic neoplasias. However, other closely related Streptococcal strains, such as <em>S. pasterianus …
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Elucidating Pseudomonas aeruginosa virulence gene regulation by the ribbon-helix-helix transcription factor AmrZ
… to immunosuppressed patients, including endocarditis, microbial keratitis of the eye, pneumonia, urinary tract infections, and chronic lung infection in patients with cystic fibrosis. The underlying cause of the severity of these infections is due in part to the arsenal of virulence …
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Effect of iron and haemoglobin on Staphylococcus aureus biofilms
… ‘silently’ harmful virulence traits, leading to endocarditis, central line-associated bloodstream infections, ventilator associated pneumonia, implant-related infection and surgical site infections among others. Biofilms are bacterial aggregations embedded in an extracellular matrix with specific …
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Functional Characterization of the Streptococcus sanguinis com Regulon
… sanguinis is also a leading cause of infective endocarditis (IE), a potentially lethal infection of the cardiac valves. S. sanguinis possesses genetic competence, the ability to acquire exogenous DNA into its genome. In the well characterized system of S. pneumoniae, genetic competence requires …
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Haemorrhage and Other Complications in Pregnant Women on Anticoagulation for Mechanical Heart Valves; a Prospective Observational Cohort Study
… six major haemorrhages, one case of infective endocarditis and three ischaemic strokes. Ten pregnancies had poor foetal outcomes (six miscarriages, three terminations, one early neonatal death). Twenty patients required more than 30 days’ hospitalisation, and 15 required three or more …
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