Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 33 for “"end stage kidney disease"”.
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Assessing the palliative care needs of end stage kidney disease patients in a tertiary hospital in Nigeria
Background: Worldwide, end-stage kidney disease (ESKD) is associated with high morbidity and mortality. Currently, the incidence of ESKD in Nigeria is about 1.6% -12.4% and is higher amongst 25-45 year-olds, implying that ESKD indirectly affects the economic productivity of the nation negatively. …
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Evaluation of Genetic Variants Influencing Susceptibility to Type 2 Diabetes Associated End-Stage Kidney Disease and Associated Phenotypes
… genetic link between type 2 diabetes associated end-stage kidney disease (T2D-ESKD) and African ancestry. Incidence and prevalence of T2D-ESKD, in addition to non-diabetic forms of ESKD, are markedly higher in African Americans compared to all other ethnicities even after adjustment for …
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Development and feasibility of an arts-based intervention for patients with end-stage kidney disease whilst receiving haemodialysis
Introduction:<br/><br/>End stage kidney disease (ESKD) is a life changing illness. Many patients require<br/>haemodialysis, a treatment that involves patients attending hospital three times a week for four hours each time. This treatment impacts profoundly on quality of life (Ho and Li, 2016) and …
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An exploration into nephrology nurses' lived experiences of caring for dying patients with end stage kidney disease following withdrawal of dialysis
… terms with the reality of their own death. Recommendations are offered to address the educational aspects of death and dying for nephrology nurses. This study endorses the need for further research into patients with ESKD ‘end-of-life’ which can influence how healthcare professionals should treat …
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Fatigue and self-management strategies among patients with end-stage kidney disease (ESKD) receiving haemodialysis: a prospective qualitative exploration conducted in the Sultanate of Oman
… debilitating symptom among patients with end-stage kidney disease (ESKD) receiving haemodialysis is fatigue. Fatigue impacts upon daily living activities, social functioning and psychological wellbeing, leading to poor quality of life. Across the Gulf States, up to 85% of patients …
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Barriers and Facilitators to Hemodialysis Access and Utilization Among Patients with End-Stage Kidney Disease in Ghana: A Mixed-Methods Study from the Perspectives of Patients, Providers, and Administrators.
ABSTRACT Background: Chronic kidney disease (CKD) is a major and growing public health issue in Ghana, with a prevalence of 13.3%. Many individuals with CKD progress to end-stage kidney disease (ESKD), for which hemodialysis is the principal lifesaving treatment. However, access to and utilization …
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Antihypertensive effects of sulforaphane
… and conditions such as stroke, heart failure and end–stage kidney disease, which results in increased cardiovascular (CV) morbidity and mortality. Among the patients receiving antihypertensive treatment, the level of adequate blood pressure (BP) control (
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Single-sided magnetic resonance sensors for clinical detection of volume status
… to regulate volume status. In each of these disease states, the body loses some ability to regulate fluid balance and maintain an euvolemic state. Deviations from euvolemia have been shown to increase morbidity and mortality. The ability to detect pre-symptomatic changes in volume status …
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The role of diet therapy in chronic kidney disease
Background Chronic kidney disease (CKD) is a condition characterized by gradual loss of kidney function over time. Millions of adults have CKD and those who have diabetes, hypertension, and family history of kidney failure are at highest risk of its development. Patients may develop comorbidities, …
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Evaluation of genetic variants for Type 2 diabetes associated kidney disease in African Americans
End-stage kidney disease (ESKD) is a significant public health problem in the U.S., disproportionately affecting African Americans (AAs; 1,003 per million/year) at 3.3-fold higher incidence rate than European Americans (301 per million/year), and 2-fold higher than Native Americans (499 per …
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GENETIC AND BIOCHEMICAL ANALYSIS OF TYPE 2 DIABETES AND DIABETIC COMPLICATIONS
… associated with T2D include cardiovascular disease (CVD), nephropathy or end-stage kidney disease (ESKD), and cognitive decline. CVD is the most common complication with up to 65% of individuals with T2D dying due to CVD. Individuals with T2D are 2 – 4 times more likely to die due to CVD …
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Association of variants in APOL1, MYH9 and HMOX1 WITH micro-Albuminuria among Sickle Cell disease patients from Cameroon
Introduction: Sickle Cell Disease (SCD) is a monogenic, multi-organ hemoglobinopathy disorder that is highly prevalent in Africa, with nearly 300 000 newborn cases per year. The underlying pathophysiological mechanism of the disease involves alteration of the normal soft and biconcave disc shape of …
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Recovery of Balance and Lower Extremity Joint Contributions in Total Ankle Arthroplasty Patients
… function in the affected limb on the order of end-stage hip arthrosis, end-stage kidney disease, and congestive heart failure. Total ankle replacement is a viable surgical option for treating end-stage ankle arthritis, but few have studied its effects on balance over time. Therefore, the …
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Normalization of Cerebral Blood Flow, Neurochemicals, and White Matter Integrity After Kidney Transplantation
Background: Chronic kidney disease (CKD) is associated with abnormalities in cerebral blood flow (CBF), cerebral neurochemical concentrations and white matter integrity, each of which are associated with adverse clinical consequences in the non-CKD population, and may explain the high prevalence of …
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Clinico-pathological characteristics and outcomes of nephrology adolescents and young adults in Cape Town: a single centre study
… Worldwide, there is a paucity of data on AYA kidney disease and outcomes. This study evaluates kidney outcomes, survival and challenges faced by AYA in a South African setting. Methods This 5-year retrospective study included AYA [aged 10-24] with chronic kidney disease, at a tertiary …
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Renal allograft biopsies at Groote Schuur Hospital: a histopathologic descriptive study with molecular insights
Background: Kidney transplantation is the definitive treatment for end-stage kidney disease. Immune-mediated rejection remains a barrier to success. It is diagnosed through the Banff classification, which incorporates histopathology and biomarkers (C4d/donor specific antibodies (DSA)). In …
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Clinico-pathological correlation and outcome in patients with mesangioproliferative glomerulonephritis in Cape Town: A single centre study
Background Glomerulonephritis is a major cause of end-stage kidney disease (ESRD) in Africa. There is scanty data on the clinico-pathological characteristics and outcome of the mesangioproliferative glomerulonephritides in Africa, despite the non-IgA subtype being reported as a common cause of …
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Patient-Centered Hemodialysis Nursing Care: An Interpretive Description
… nursing care could benefit people with end-stage kidney disease (ESKD) however the philosophical ideals of the approach may not consistently align with the everyday reality of hemodialysis nursing. Purpose of Study The study purpose was to describe the experiences and perspectives of …
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A comparison of clinical, biochemical, and histological characteristics as well as evaluation of outcomes of patient with mesangiovapillary glomerulonephritis (MCGN) in HIV positive and negative patients at a tertiary hospital in Cape Town, South Africa
… and the co-existence of MCGN and HIV may affect kidney prognosis. The aim of this study was to compare the clinical and biochemical features between PWH and HIV-negative individuals with a diagnosis of MCGN and to review kidney function and survival. Materials and Methods A retrospective study …
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Role of T cells and cytokines in the induction of tolerance to renal tubular antigen in active Heymann nephritis
… in humans, and many patients progress to end-stage kidney disease. The best available animal model of MN is active Heymann nephritis (HN) in which rats are immunized with renal tubular antigen (RTA) in complete Freund's adjuvant (CFA). Rats develop heavy proteinuria, a key measure of …
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