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Showing 1 to 1 of 1 for “"end binding protein 1"”.
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Replacement of Val3 In Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability, Complexes of Sperm Whale Myoglobin G65T With Phenol and Ethylene Glycol, and Structure of A Fragment of Human End-Binding Protein 1 (Eb1)
… has been considered to play a primary role in protein turnover but not in catalytic activity. Two mutants, V3L and V3F, have strongly compromised dUMP binding, with Km,app values increased by factors of 47 and 58, respectively. For V3L, this observation can be explained by stabilization of the …