Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"embryo research"”.
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Anne McLaren and the Human Embryo Research Debates in Britain, 1982–1990: Sociological Biography in the Analysis of Public Debate
… parliamentary debates on human fertilisation and embryology (HF&E) in Britain between 1982 and the resulting Act in 1990. A focus on McLaren’s contributions to these debates elucidates how the case in favour of embryo research was constructed. Drawing especially on the use of the contested term …
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Medical biotechnology law in South Africa : a human rights analysis of selected topics
… medical biotechnology subjects, namely human embryo research, the use of human gametes, autologous tem cell therapy, and private stem cell banking. In all four cases, my analyses give specific prominence to two research themes: first, human dignity as touchstone of the South African human …
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WNT signalling in the patterning of human gastruloids
… Because of the 14-day rule imposed on human embryo research, no experimental studies have been conducted beyond this date. The derivation of human embryonic stem cells (hESCs) has opened up numerous opportunities for studying early cell fate decisions and signals involved in this process. In …
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Investigating the consequences of chromosome abnormalities arising during pre-implantation development of the mouse
The majority of human pre-implantation embryos created through in vitro fertilization (IVF) are mosaic as they are constituted of a mixture of diploid and aneuploid cells. Chromosome abnormalities are widely believed to contribute towards the relatively low success rates of IVF treatment. …
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Illuminating the Black Box: Defining and Modeling Peri-Implantation Human Embryogenesis
… However, the inaccessibility of human embryos during implantation has limited our understanding of these stages. In this Thesis, I interrogated multiple aspects of human peri-implantation development. Utilizing human embryos cultured through implantation in vitro, I first generated a …
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Pluripotency and patterning in nonhuman primate embryogenesis
Pluripotent cells of the embryo have the remarkable ability to form all somatic tissues and the germ line. Mice have long provided a framework for our understanding of this property of the early embryo. However, primate embryogenesis differs in anatomical architecture, developmental timing, and …
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Designer Genes: An analysis of a theoretical framework for policy proposals in relation to genetic engineering as a reproductive technology
… for policy makers. If gene therapy (or even embryo selection) becomes common practice, we must look not only to creating policies that protect the interests of individuals in the legal and social realms, but consideration must also be given to the equality of opportunity in the genetic sense. …