Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"embryo implantation"”.
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Smooth muscle titin in embryo implantation and angiogenesis
… im glatten Muskel des Uterus entfernt. Die Embryo-Implantationsstellen der meisten schwangeren Knockout-Tiere waren fehllokalisiert, lagen zu dicht oder waren in der Anzahl reduziert. Zudem war die Entwicklung des Uterus zu Beginn der Schwangerschaft bei Knockout-Mäusen verzögert. …
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Role of Msx homeobox genes in uterus during embryo implantation
Implantation of the embryo into the wall of the uterus is a crucial event in mammalian embryogenesis. This complex event involves a series of interactions between the developing embryo and the receptive endometrium ultimately leading to successful establishment of pregnancy. The sequential events …
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Trophinin: Expression and Regulation in the Porcine Uterus and Embryo During the Time of Embryo Implantation
… through out the uterus and the presence of an embryo had no effect on expression. Trophinin mRNA transcripts were detected at day 14 of the estrous cycle, and expression was maintained until day 24 in animals that had established pregnancy. Porcine embryos show expression of trophinin around …
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The role of ERα in the uterus during embryo implantation and in the ovary during ovarian tumorigenesis
… downstream target Hif2alpha in the uterus during embryo implantation. The later part of the dissertation discusses the role that ERalpha plays in ovarian tumorigenesis. Both humans and rodents exhibit hemochorial placentation, an invasive form of embryo implantation which is characterized by …
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The Role of Glucose -6 -Phosphate Isomerase in Implantation in the Ferret (Mustela Putorius)
I concluded that GPI is the 60 kilodalton implantation protein. GPI is produced and secreted by ferret CL on days 6--9 of pregnancy in ferrets and is required for embryo implantation. Further study is needed to determine whether prolactin, which is also required for implantation, affects GPI …
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Purification and Characterization of an Anti-Basigin Monoclonal Antibody: Application to the Study of Human Uterine Cells and Tissues
… increased by over 15% (Sun et al., 2019). An embryo's failure to implant into the uterus is the primary cause of early pregnancy loss. Several studies have identified molecules necessary for successful implantation, but their function during implantation remains poorly understood (S. Zhang et …
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The Role of PRICKLE1 in the Regulation of Uterine Structure and Physiology
… the endometrium, is critical for successful implantation and pregnancy. The smooth muscle cells of the myometrial layer are organized into several sub-layers with longitudinal and circular orientations and help to facilitate uterine contractions and sperm transport. The specific cellular …
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Progesterone control of human endometrial cells
… is one such event and is considered essential to embryo implantation and to the maintenance of pregnancy. In humans these changes are most dramatic in the stromal compartment and are influenced by progesterone, secreted by the Corpus Luteum (CL). This hormone is believed to be the main factor …
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A two-pronged approach towards the development of novel therapeutics for advanced endometrial cancer
… external insult and plays an important role in embryo implantation. EGFR is a receptor tyrosine kinase that influences cellular proliferation, migration and apoptosis. MUC1 increases EGFR gene expression, mRNA levels, protein levels and signaling in endometrial cancer cell lines. Consequently, …
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Analysis of the Role of the Transcription Factor-C/ebpbeta in Implantation
… transformation, an essential prerequisite for embryo implantation, are poorly understood. We previously identified the transcription factor C/EBPbeta as a target of steroid hormone regulation in the uterus. The uteri of C/EBPbeta-null mice failed to undergo decidualization, indicating a …
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Analysis of the Role of the Transcription Factor C/EBPbeta in Controlling Uterine Functions During Early Pregnancy
Embryo implantation into the endometrium is a complex biological process involving the integration of steroid hormone signaling, endometrial tissue remodeling and maternal-fetal communications. A successful pregnancy is the outcome of the timely integration of these events during the early stages …
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Analysis of the role of the transcription factor C/EBPβ in controlling uterine functions during early pregnancy
Embryo implantation into the endometrium is a complex biological process involving the integration of steroid hormone signaling, endometrial tissue remodeling and maternal- fetal communications. A successful pregnancy is the outcome of the timely integration of these events during the early stages …
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Analysis of the role of the transcription factor-C/EBPβ in implantation
… transformation, an essential prerequisite for embryo implantation, are poorly understood. We previously identified the transcription factor C/EBPβ as a target of steroid hormone regulation in the uterus. The uteri of C/EBPβ–null mice failed to undergo decidualization, indicating a critical role …
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Role of glucose transporter 1 during pregnancy
… intricate relationship between mother and fetus. Implantation and decidualization are characteristic features of early pregnancy. Events during early pregnancy are regulated by steroid hormones, estrogen and progesterone. Our recent studies have indicated that Hif2α is induced by estrogen in the …
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Steroid Hormone Regulation of Implantation
… (P) coordinate to regulate the process of embryo implantation, the process by which embryo attaches to the uterine epithelium. The uterus in response to the implanting embryo undergoes various changes to help create a suitable environment for the implanting embryo. E and P regulate this …
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Role of Sox9 In Uterine Gland Development and Disease Initiation
… reproductive tract (FRT) develops midway through embryogenesis, and consists of oviducts, uterine horns, cervix and upper part of the vagina. The uterine horns are composed of an epithelial layer, luminal (LE) and glandular epithelium (GE), surrounded by a mesenchymal layer, the stroma and …
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Mechanisms underlying establishment and maintenance of pregnancy
Implantation is initiated when an embryo attaches to the uterine luminal epithelium and subsequently penetrates into the underlying stroma to firmly embed in the endometrium. These events are followed by the formation of an extensive vascular network in the stroma that supports embryonic growth and …
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A Genomic Perspective on Early Embryo Development in Cattle
In vitro embryo production (IVP) has revolutionized the cattle industry, but it still faces efficiency limitations compared to in vivo embryo production. With a major impact on it, a proper transcriptome profile is crucial for an embryo to undergo pre-implantation development and become …
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Trophoblast specification and differentiation potential in early human and non-human primate embryogenesis
Implantation is mediated by trophoblast, the outer layer of the early embryo. Trophoblast is an extraembryonic tissue that gives rise to the placenta, which sustains fetal growth and development. Human embryo implantation and early trophoblast development have remained elusive due to the …
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The Effect of the Conceptus on Endometrial Angiogenesis and Immune Cell Populations During Implantation
… establishment of pregnancy is after the onset of implantation but before the establishment of the placenta. In fact, evidence strongly suggests that when abnormalities occur during this period of pregnancy in humans there may be dire consequences such as termination of pregnancy, pre-eclampsia …
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